RuPhos
Tech Serve Solutions (TSS) offers RuPhos (CAS: 787618-22-8), a chemical compound with the formula C30H43O2P and a molecular weight of 466.64 g/mol. This bulky phosphine ligand is instrumental in palladium-catalyzed cross-coupling reactions, particularly for the coupling of aminoethyltrifluoroborates with electron-poor aryl bromides. Its efficacy makes it a valuable reagent in synthetic organic chemistry and catalysis research.
- IUPAC
- 2-Dicyclohexylphosphino-2′,6′-diisopropoxybiphenyl
- Synonyms
- 2-Dicyclohexylphosphino-2',6'-diisopropoxybiphenyl
Palladium-Catalyzed Cross-Coupling
RuPhos serves as a crucial bulky phosphine ligand in palladium-catalyzed cross-coupling reactions. It is particularly effective in facilitating the coupling of aminoethyltrifluoroborates with electron-poor aryl bromides, enabling efficient formation of new carbon-carbon bonds.
Organic Synthesis
As a key component in modern synthetic methodologies, RuPhos enables complex molecular constructions. Its specific electronic and steric properties are advantageous in various transformations requiring palladium catalysis, such as Suzuki-Miyaura and Buchwald-Hartwig couplings.
Catalysis Research
This compound is widely employed in research settings to develop and optimise catalytic systems. Its application aids in exploring novel reaction pathways and improving the efficiency and scope of existing catalytic processes in both academia and industry.
| Molecular weight | 466.64 |
|---|---|
| Empirical formula | C30H43O2P |
| Assay | 95% |
| Impurities tested | 1-5% Bis(2′,6′-Diisopropoxybiphenyl)cyclohexylphosphine |
| Application | Bulky phosphine ligand used in a palladium-catalyzed cross-coupling of aminoethyltrifluoroborates with electron-poor aryl bromides.1 |
| Melting point | 123-126 °C |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
- H413May cause long-lasting harmful effects to aquatic life
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Ligand For | ArylationsBuchwald-Hartwig Cross Coupling ReactionNegishi CouplingSonogashira CouplingSuzuki-Miyaura Coupling |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is RuPhos primarily used for?
+
RuPhos is primarily used as a bulky phosphine ligand in palladium-catalyzed cross-coupling reactions, notably for the coupling of aminoethyltrifluoroborates with electron-poor aryl bromides and other arylations.
What is the CAS number and chemical formula for RuPhos?
+
The CAS number for RuPhos is 787618-22-8, and its chemical formula is C30H43O2P.
What grade and purity does Tech Serve Solutions supply for RuPhos?
+
Tech Serve Solutions supplies RuPhos with an assay of 95%. This product is intended for research and laboratory use and is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should RuPhos be handled safely?
+
RuPhos is classified as harmful if swallowed, in contact with skin, or if inhaled (H302, H312, H332), and may cause long-lasting harmful effects to aquatic life (H413). Handle with appropriate personal protective equipment (P280) in a well-ventilated area.
Is RuPhos a controlled substance?
+
Based on the provided data, RuPhos is not indicated as a controlled substance. However, users should always verify local regulations.
How can I request a sample or quote for RuPhos?
+
To request a sample or a quote for RuPhos, please contact the Tech Serve Solutions sales team through our website or by phone, providing the product name and CAS number (787618-22-8).
How is RuPhos packed and exported?
+
RuPhos is carefully packed to ensure stability during transit and is available for export globally by Tech Serve Solutions. Specific packaging details are confirmed upon order.
▶ Related products
Benzeneruthenium(II) chloride dimer
Ru2(C6H6)2Cl4
Catalysis & Inorganic
Benzoylferrocene
C17H14FeO
Catalysis & Inorganic
Benzyldiphenylphosphine
C6H5CH2P(C6H5)2
Catalysis & Inorganic
Beryllium
Be
Catalysis & Inorganic
Beryllium oxide
BeO
Catalysis & Inorganic![Bicyclo[2.2.1]hepta-2,5-diene-rhodium(I) chloride dimer — chemical structure, CAS 12257-42-0; Catalysis & Inorganic, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F12257-42-0.png&w=3840&q=75)
Bicyclo[2.2.1]hepta-2,5-diene-rhodium(I) chloride dimer
Catalysis & Inorganic
![Bis[(10,11-η)-5-[(11bS)-dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-yl- κP4]-5H-dibenz[b,f]azepine]rhodium(I) tetrafluorobo — chemical structure, CAS 1228149-03-8; Catalysis & Inorganic, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F1228149-03-8.png&w=3840&q=75)
Bis[(10,11-η)-5-[(11bS)-dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-yl- κP4]-5H-dibenz[b,f]azepine]rhodium(I) tetrafluorobo
1-d:1′
Catalysis & Inorganic![Bis[(2-dimethylamino)phenyl]amine nickel(II) chloride (C16H20ClN3Ni) — chemical structure, CAS 1033772-47-2; Catalysis & Inorganic, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F1033772-47-2.png&w=3840&q=75)
Bis[(2-dimethylamino)phenyl]amine nickel(II) chloride
C16H20ClN3Ni
Catalysis & Inorganic▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis