Rhodanine
Rhodanine (CAS: 141-84-4; C3H3NOS2) is a heterocyclic organic compound with a molecular weight of 133.19. Known as 2-Thioxo-4-thiazolidinone, it presents as a solid. Rhodanine is primarily utilised in chemical synthesis as a versatile building block, particularly in the preparation of various thiazole derivatives and related heterocyclic structures. Its applications extend to research in organic chemistry and biochemical assays.
- IUPAC
- 2-Thioxo-4-thiazolidinone
- Synonyms
- 2-Thioxo-4-thiazolidinone

Tannase Assay
Rhodanine has been documented for use in tannase assays. It aids in the evaluation of tannin-degrading fungi within culture media, providing a method for assessing enzymatic activity.
Chemical Synthesis
As a key building block, Rhodanine is employed in the synthesis of diverse organic molecules. Its structure is integral to the formation of heterocyclic compounds, especially those containing the thiazole moiety, making it valuable in medicinal chemistry research.
Research Reagent
Rhodanine serves as a laboratory reagent for academic and industrial research. It is instrumental in exploring novel chemical pathways and developing new synthetic methodologies in organic chemistry.
| Molecular weight | 133.19 |
|---|---|
| Empirical formula | C3H3NOS2 |
| Assay | 97% |
| Solubility | methanol: soluble2.5%, clear (yellow-green to orange-brown) |
| Application | Rhodanine has been used in tannase assay in cultures of tannin degrading fungi1. |
| Melting point | 165-169 °C(lit.) |


Hazard statements
- H302Harmful if swallowed
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-41 |
| Safety statements (S) | 22-26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Rhodanine used for?
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Rhodanine (CAS: 141-84-4) is primarily used as a building block in chemical synthesis, particularly for creating thiazole derivatives and other heterocyclic compounds. It also finds application in biochemical assays, such as the tannase assay.
What is the CAS number and formula for Rhodanine?
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The CAS number for Rhodanine is 141-84-4, and its empirical formula is C3H3NOS2.
What grade and purity does Tech Serve Solutions supply for Rhodanine?
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Tech Serve Solutions supplies Rhodanine with an assay of 97%. We do not represent this product as meeting any specific pharmacopoeia standards such as USP, BP, or EP, and it is typically considered for research or technical applications.
How should Rhodanine be handled safely?
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Rhodanine is classified with Danger signal word, presenting hazards H302 (Harmful if swallowed) and H318 (Causes serious eye damage). Appropriate personal protective equipment, including a dust mask (N95 type), eyeshields, face shields, and gloves, is essential. Handle in a well-ventilated area, avoid dust formation, and wear protective clothing.
How is Rhodanine packed, shipped, and exported by TSS?
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Tech Serve Solutions securely packs and prepares Rhodanine for global export, adhering to all relevant shipping regulations for chemical compounds. Specific packaging details can be provided upon request.
How can I request a sample or quote for Rhodanine?
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To request a sample or a quote for Rhodanine, please contact our sales team through the website or by phone, providing your contact details and the quantity required.
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