Radicicol from Diheterospora chlamydosporia
Radicicol from Diheterospora chlamydosporia (CAS: 12772-57-5; C18H17ClO6) is a yellow solid compound with a molecular weight of 364.78. This bioactive molecule functions as an inhibitor of heat shock protein 90 (HSP90). It is utilised in biochemical research and cancer studies, particularly for its antineoplastic properties and its role in cell signalling pathways. Radicicol is also noted for its antifungal activity.
- IUPAC
- Monorden,[1aS-(1aR*,2Z,4E,14*,15aR*)]-8-Chloro-1a,14,15,15a-tetrahydro-9,11-dihydroxy-14-methyl-6H-oxireno[e][2]benzoxacyclotetradecin-6,12(7H)-dione
- Synonyms
- Monorden[1aS-(1aR*,2Z,4E,14*,15aR*)]-8-Chloro-1a,14,15,15a-tetrahydro-9,11-dihydroxy-14-methyl-6H-oxireno[e][2]benzoxacyclotetradecin-6,12(7H)-dione
Antineoplastic Research
Radicicol serves as a valuable tool in cancer research due to its ability to inhibit HSP90, a protein crucial for the survival and proliferation of cancer cells. It is explored for its potential chemopreventive and antineoplastic effects.
Cell Biology Studies
This compound is employed in cell biology to investigate cellular processes, including cell signalling pathways and the mechanisms underlying cell growth and survival, particularly in relation to stress responses.
Enzyme Inhibition Studies
As an enzyme inhibitor, Radicicol is used to study the function and regulation of target enzymes, such as HSP90, providing insights into their roles in various biological processes.
Antifungal Research
The antifungal properties of Radicicol make it a subject of study for potential applications in combating fungal infections and understanding fungal biology.
| Molecular weight | 364.78 |
|---|---|
| Empirical formula | C18H17ClO6 |
| Form | solid |
| Colour | yellow |
| Solubility | ethanol: soluble10 mg/mL |
| Storage temperature | −20°C |
Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H340May cause genetic defects
- H350May cause cancer
Precautionary statements
- P201Obtain special instructions before use
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P305IF IN EYES
- P308IF exposed or concerned
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 45-46-22-36/37/38 |
| Safety statements (S) | 53-26-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... HSP90AA1(3320), SRC(6714)rat ... Src(83805) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Radicicol from Diheterospora chlamydosporia used for?
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Radicicol from Diheterospora chlamydosporia is primarily used in biochemical research, cancer research, cell biology studies, and for investigating its antifungal properties and enzyme inhibitory mechanisms, particularly against HSP90.
What is the CAS number and formula for Radicicol?
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The CAS number for Radicicol from Diheterospora chlamydosporia is 12772-57-5, and its empirical formula is C18H17ClO6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Radicicol as a yellow solid. The specific assay or purity is determined by the product specifications; we do not represent this product as USP, BP, or EP grade.
How should Radicicol be handled safely?
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Radicicol is a Danger substance. It is toxic if swallowed, causes skin and serious eye irritation, may cause respiratory irritation, and is suspected of causing genetic defects and cancer. Handle with appropriate personal protective equipment in a well-ventilated area and follow all safety precautions, including P201, P261, P301 + P310, P305 + P351 + P338, and P308 + P313.
How is Radicicol packed and exported?
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Radicicol is typically supplied as a solid and shipped according to international regulations for hazardous materials (UN 2811 6.1 / PGIII). Tech Serve Solutions is a global supplier and exporter.
How can I request a quote or sample for Radicicol?
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To request a quote or sample for Radicicol, please contact the Tech Serve Solutions sales team through our website or via direct inquiry.
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