(R)-(+)-α-Methylvaline
(R)-(+)-α-Methylvaline (CAS: 53940-82-2; Formula: C6H13NO2; MW: 131.17) is a non-proteinogenic amino acid derivative. It serves as a valuable chiral building block in organic synthesis, particularly within peptide chemistry and the development of novel chemical entities. Its specific stereochemistry makes it crucial for creating molecules with defined three-dimensional structures for research and development purposes.
- IUPAC
- α-Me-D-Val-OH,α-Methyl-D-valine
Chiral Synthesis
Utilised as a chiral auxiliary or building block in asymmetric synthesis, enabling the construction of enantiomerically pure compounds essential in pharmaceutical research.
Peptide Chemistry
Incorporated into unnatural peptide sequences to modify biological activity, stability, or receptor binding properties. It offers a unique structural motif compared to natural amino acids.
Chemical Biology Research
Employed in the synthesis of probes and labelled molecules for studying biological pathways and protein interactions, contributing to a deeper understanding of biological systems.
Drug Discovery Intermediates
Serves as a key intermediate in the synthetic routes towards novel therapeutic agents, where its specific chirality is critical for pharmacological efficacy.
| Molecular weight | 131.17 |
|---|---|
| Empirical formula | C6H13NO2 |
| Assay | ≥98.5% (TLC)99% |
| Optical activity | [α]/D +3.5±0.5°, c = 1% in H2O |
| Impurities tested | ≤0.2% water |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(+)-α-Methylvaline used for?
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(R)-(+)-α-Methylvaline is used in chiral synthesis, peptide chemistry, chemical biology research, and as an intermediate in drug discovery.
What is the CAS number and molecular formula for (R)-(+)-α-Methylvaline?
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The CAS number is 53940-82-2, and the molecular formula is C6H13NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(+)-α-Methylvaline with an assay of ≥98.5% (TLC) and 99%, with impurities of ≤0.2% water. This is a technical/research grade, and TSS does not represent it as USP, BP, or EP grade.
How should (R)-(+)-α-Methylvaline be handled safely?
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Handling requires the use of eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. This compound has a WGK Germany classification of 3.
Does Tech Serve Solutions export (R)-(+)-α-Methylvaline?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including (R)-(+)-α-Methylvaline.
How can I request a sample or quote for (R)-(+)-α-Methylvaline?
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Please contact our sales team through the website to request a sample or a quotation for (R)-(+)-α-Methylvaline.
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