(R)-(+)-α-Methyl-4-pyridinemethanol
(R)-(+)-α-Methyl-4-pyridinemethanol (CAS 27854-88-2), with the molecular formula C7H9NO and a molecular weight of 123.15 g/mol, is a chiral alcohol derived from pyridine. This enantiomerically pure compound is valuable in asymmetric synthesis as a chiral building block. Its defined stereochemistry makes it essential for creating complex chiral molecules, particularly in the pharmaceutical and fine chemical industries.
- IUPAC
- (R)-(+)-1-(4-Pyridyl)ethanol
- Synonyms
- (R)-(+)-1-(4-Pyridyl)ethanol

Chiral Building Block in Organic Synthesis
Utilised as a key chiral intermediate in the synthesis of complex organic molecules, particularly pharmaceuticals and agrochemicals where specific stereochemistry is crucial for biological activity.
Asymmetric Synthesis
Employed in asymmetric reactions to introduce or control chirality, enabling the production of enantiomerically pure compounds critical for drug discovery and development.
Chiral Resolution Reagent
Can be used as a resolving agent for the separation of racemic mixtures, facilitating the isolation of specific enantiomers.
Research and Development
A valuable reagent in academic and industrial research laboratories for exploring new synthetic routes and developing novel chemical entities.
| Molecular weight | 123.15 |
|---|---|
| Empirical formula | C7H9NO |
| Assay | 99% |
| Grade | puriss. |
| Optical activity | [α]20/D +55°, c = 1 in chloroform |
| Optical purity | ee: 98% (GLC) |
| Melting point | 67-69 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(+)-α-Methyl-4-pyridinemethanol used for?
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This compound is primarily used as a chiral building block in asymmetric synthesis, particularly in the pharmaceutical and fine chemical industries, and can also serve as a chiral resolution reagent.
What are the CAS number and formula for (R)-(+)-α-Methyl-4-pyridinemethanol?
+
The CAS number is 27854-88-2, and the empirical formula is C7H9NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of 99% and a grade of puriss. We do not represent it as USP, BP, or EP grade unless explicitly stated in the product data.
How should (R)-(+)-α-Methyl-4-pyridinemethanol be handled?
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It is a warning substance (GHS07) that may cause skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). Use a dust mask type N95 (US), wear eyeshields and gloves, and ensure good ventilation. In case of eye contact, rinse cautiously with water for several minutes (P305 + P351 + P338).
Is this chemical suitable for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals and laboratory reagents.
How can I request a sample or quote?
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Please contact our sales department directly through our website or by phone to request a sample or a quotation for (R)-(+)-α-Methyl-4-pyridinemethanol.
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