(R)-Boc-3-(trifluoromethyl)-β-Phe-OH
(R)-Boc-3-(trifluoromethyl)-β-Phe-OH (CAS: 501015-18-5) is a valuable unnatural amino acid derivative with the empirical formula C15H18F3NO4 and a molecular weight of 333.30 g/mol. This compound is a key building block in chemical synthesis and peptide chemistry. Its structure, featuring a trifluoromethyl group and a Boc-protected amine, makes it particularly useful for introducing specific properties into peptides and other organic molecules, enabling advancements in chemical biology research.
- IUPAC
- (R)-3-(Boc-amino)-3-[3-(trifluoromethyl)phenyl]propionic acid,Boc-3-(trifluoromethyl)-L-β-phenylalanine

Chemical Synthesis
Serves as a chiral building block for the synthesis of complex organic molecules. The trifluoromethyl group can impart unique electronic and lipophilic properties to target compounds.
Peptide Chemistry
Incorporated into peptide sequences to create peptidomimetics or peptides with enhanced stability and altered biological activity. The unnatural beta-amino acid structure offers distinct conformational possibilities.
Chemical Biology Research
Used in the design and synthesis of novel probes and biologically active molecules for studying cellular processes and protein function.
Unnatural Amino Acid Derivatives
A specialized reagent for researchers developing new amino acid-based materials or pharmaceuticals. Its structure is valuable for structure-activity relationship (SAR) studies.
| Molecular weight | 333.30 |
|---|---|
| Empirical formula | C15H18F3NO4 |
| Assay | ≥95.0% (HPLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-Boc-3-(trifluoromethyl)-β-Phe-OH used for?
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(R)-Boc-3-(trifluoromethyl)-β-Phe-OH is used as a building block in chemical synthesis, peptide chemistry, chemical biology research, and for creating unnatural amino acid derivatives.
What is the CAS number and formula for (R)-Boc-3-(trifluoromethyl)-β-Phe-OH?
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The CAS number is 501015-18-5 and the empirical formula is C15H18F3NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-Boc-3-(trifluoromethyl)-β-Phe-OH with a minimum purity of 95.0% as determined by HPLC. This product is supplied for research and development purposes and is not intended for USP, BP, EP, or other pharmacopoeia grades.
What are the safety and handling recommendations for this product?
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This compound is classified under WGK 3 in Germany. Appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter, should be used during handling to prevent exposure.
Can Tech Serve Solutions export this chemical globally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents.
How can I request a sample or quote for (R)-Boc-3-(trifluoromethyl)-β-Phe-OH?
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Please contact our sales team through our website to request a sample or obtain a quotation for (R)-Boc-3-(trifluoromethyl)-β-Phe-OH.
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