(R)-(−)-1-Aminoindane
(R)-(−)-1-Aminoindane (CAS: 10277-74-4, C9H11N) is a chiral amine with a molecular weight of 133.19 g/mol. This compound is a valuable building block in asymmetric synthesis, finding utility in the preparation of stereochemically defined molecules. Its optical activity and defined stereochemistry make it a sought-after intermediate in organic chemistry and pharmaceutical research.
- IUPAC
- (R)-(−)-1-Indanamine
Asymmetric Synthesis
(R)-(−)-1-Aminoindane serves as a chiral auxiliary or building block in the synthesis of enantiomerically pure compounds. Its defined stereocenter is crucial for controlling the chirality of target molecules.
Pharmaceutical Intermediates
This amine is employed in the development and synthesis of active pharmaceutical ingredients (APIs) where specific stereochemistry is required for biological activity. It is a key component in constructing complex chiral drugs.
Organic Building Block
As a versatile organic building block, (R)-(−)-1-Aminoindane can be incorporated into a wide array of organic structures through various chemical transformations. Its functional groups allow for diverse synthetic pathways.
| Molecular weight | 133.19 |
|---|---|
| Empirical formula | C9H11N |
| Assay | ≥98.5% (GC)99% |
| Boiling point | 96-97 °C/8 mmHg(lit.) |
| Density | 1.038 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.562(lit.) |
| Optical activity | [α]20/D −16.5°, c = 1.5 in methanol |
| Melting point | 15 °C(lit.) |
| Optical purity | enantiomeric excess: ≥98.5% |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H411Toxic to aquatic life with long-lasting effects
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P273Avoid release to the environment
- P305IF IN EYES
| Flash point | 94 °C / 201.2 °F |
|---|---|
| Transport (UN / ADR) | UN 3082 9 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi,N |
| Risk statements (R) | 36/37/38-51/53 |
| Safety statements (S) | 26-36-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(−)-1-Aminoindane used for?
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(R)-(−)-1-Aminoindane is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in the synthesis of pharmaceuticals and other complex organic molecules requiring specific stereochemistry.
What is the CAS number and molecular formula for (R)-(−)-1-Aminoindane?
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The CAS number for (R)-(−)-1-Aminoindane is 10277-74-4, and its molecular formula is C9H11N.
What grade and purity does Tech Serve Solutions supply for (R)-(−)-1-Aminoindane?
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Tech Serve Solutions supplies (R)-(−)-1-Aminoindane with an assay of ≥98.5% (GC) and 99% optical purity (enantiomeric excess: ≥98.5%). TSS does not represent this chemical as USP, BP, or EP grade.
How should (R)-(−)-1-Aminoindane be handled safely?
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(R)-(−)-1-Aminoindane is classified with GHS07 and GHS09 symbols, a Warning signal word, and hazards including skin irritation (H315), eye irritation (H319), respiratory irritation (H335), and toxicity to aquatic life with long-lasting effects (H411). Handle with appropriate personal protective equipment in a well-ventilated area, avoiding release to the environment. Refer to the Safety Data Sheet for comprehensive handling guidelines.
Is (R)-(−)-1-Aminoindane a controlled substance?
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The provided data does not indicate that (R)-(−)-1-Aminoindane is a controlled substance.
How is (R)-(−)-1-Aminoindane packed and shipped?
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(R)-(−)-1-Aminoindane is shipped according to regulations for UN 3082 (Class 9, PGIII). Specific packaging details are available upon request and are handled in compliance with international shipping standards for chemical export.
How can I request a quote or sample for (R)-(−)-1-Aminoindane?
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To request a quote or sample for (R)-(−)-1-Aminoindane, please visit the Tech Serve Solutions website or contact our sales department with your specific requirements.
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