6-Diazo-5-oxo-L-norleucine
6-Diazo-5-oxo-L-norleucine (CAS: 157-03-9), a diazo amino acid derivative with the chemical formula C6H9N3O3 and a molecular weight of 171.15 g/mol, is a light yellow crystalline solid. It is recognised for its role in biochemical research, particularly in studies related to cancer metabolism and glutamine pathways. Its antineoplastic properties make it a compound of interest in oncology research.
- IUPAC
- (S)-2-Amino-6-diazo-5-oxocaproic acid,DON
Biochemical Research
Utilised as a research tool in studies investigating enzyme mechanisms and metabolic pathways, especially those involving amino acid metabolism and glutamine addiction in cancer cells.
Cancer Metabolism Studies
Serves as an antineoplastic agent and immunosuppressive antibiotic in research focused on understanding and targeting cancer cell metabolism, including glutamine metabolism and oncogenesis.
Cell Biology Investigations
Employed in cell biology research to explore cellular processes affected by nutrient deprivation or altered metabolic states, contributing to fundamental biological understanding.
| Molecular weight | 171.15 |
|---|---|
| Empirical formula | C6H9N3O3 |
| Form | crystalline |
| Colour | light yellow |
| Storage temperature | −20°C |
Hazard statements
- H301Toxic if swallowed
- H311Toxic in contact with skin
- H331Toxic if inhaled
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P311Call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 23/24/25 |
| Safety statements (S) | 36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 6-Diazo-5-oxo-L-norleucine used for?
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6-Diazo-5-oxo-L-norleucine is primarily used in biochemical and cancer metabolism research. It acts as an antineoplastic agent and immunosuppressive antibiotic, particularly in studies related to glutamine metabolism and oncogenesis.
What are the CAS number and chemical formula for 6-Diazo-5-oxo-L-norleucine?
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The CAS number for 6-Diazo-5-oxo-L-norleucine is 157-03-9, and its chemical formula is C6H9N3O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 6-Diazo-5-oxo-L-norleucine as a crystalline solid. We do not specify a particular grade or purity beyond what is inherent to its nature as a research chemical and cannot represent it as USP, BP, or EP grade unless explicitly stated in the product specifications.
How should 6-Diazo-5-oxo-L-norleucine be handled safely?
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6-Diazo-5-oxo-L-norleucine is classified as a Danger substance (GHS06) and is toxic if swallowed, in contact with skin, or if inhaled (H301-H311-H331). Handling requires appropriate personal protective equipment, including eyeshields, faceshields, gloves, and a P2 respirator cartridge (EN 143). Follow stringent safety protocols as indicated by the safety data sheet and avoid exposure.
How is 6-Diazo-5-oxo-L-norleucine packed, shipped, and exported?
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This chemical is typically stored at -20°C. Packing, shipping, and export procedures adhere to international regulations for hazardous materials, considering its classification as UN 2811, Class 6.1, Packing Group III.
How can I request a sample or quote for 6-Diazo-5-oxo-L-norleucine?
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To request a sample or quote, please contact our sales department via the website or direct inquiry. Please include the product name and CAS number (157-03-9) in your request.
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