PYR-41
PYR-41 (CAS: 418805-02-4), with the empirical formula C17H13N3O7, is a chemical compound primarily utilised in cell biology research. It plays a significant role in studies concerning cell signalling, intracellular protein degradation, and cellular responses to stress, including those involving nitric oxide. Its application extends to investigations into the ubiquitin-protease system, making it a valuable reagent for understanding complex cellular pathways.
- IUPAC
- 4[4-(5-Nitro-furan-2-ylmethylene)-3,5-dioxo-pyrazolidin-1-yl]-benzoic acid ethyl ester
Cell Signalling and Neuroscience Research
PYR-41 is employed to investigate intracellular signalling cascades and their implications in neurological processes. It aids researchers in understanding how cellular communication pathways are modulated.
Intracellular Protein Degradation Studies
This compound is used to study mechanisms of protein degradation within cells, particularly those involving the ubiquitin-protease system. It assists in elucidating pathways that regulate protein turnover.
Nitric Oxide and Cell Stress Investigations
PYR-41 is applied in research focusing on cellular responses to stress, including the role of nitric oxide. It helps in characterising how cells react to and manage oxidative or other forms of stress.
Ubiquitin and Protease System Analysis
Researchers utilise PYR-41 to probe the functions and interactions within the ubiquitin-protease system. This is crucial for understanding protein homeostasis and disease mechanisms.
| Empirical formula | C17H13N3O7 |
|---|---|
| Assay | ≥98% (HPLC) |
| Solubility | DMSO: soluble5 mg/mL, clear (warmed) |
| Storage temperature | −20°C |
Hazard statements
- H302Harmful if swallowed
- H317May cause an allergic skin reaction
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-43 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is PYR-41 used for?
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PYR-41 is primarily used in cell biology research, specifically in studies related to cell signalling, intracellular protein degradation, nitric oxide and cell stress, and the ubiquitin-protease system.
What is the CAS number and empirical formula for PYR-41?
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The CAS number for PYR-41 is 418805-02-4, and its empirical formula is C17H13N3O7.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies PYR-41 with an assay of ≥98% (HPLC). TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade. It is supplied for research and laboratory use.
What are the safety considerations when handling PYR-41?
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PYR-41 is classified with a GHS07 symbol and a Warning signal word. It carries hazard statements H302 (Harmful if swallowed) and H317 (May cause an allergic skin reaction). Appropriate personal protective equipment, such as gloves and protective clothing (P280), should be worn during handling. Refer to the Safety Data Sheet for full details.
How is PYR-41 typically stored and shipped?
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PYR-41 should be stored at -20°C. It is suitable for export and is shipped according to standard chemical transport regulations.
How can I request a sample or quote for PYR-41?
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To request a sample or a quote for PYR-41, please contact the Tech Serve Solutions sales team via our website or direct email, providing your specific requirements.
Is PYR-41 soluble in common laboratory solvents?
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PYR-41 is soluble in DMSO at a concentration of 5 mg/mL, appearing clear after warming.
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