PX 12
PX 12 (CAS: 141400-58-0) is a chemical compound with the formula C7H12N2S2 and a molecular weight of 188.31 g/mol. This off-white to tan powder is primarily used in scientific research, particularly in studies related to cancer metabolism, aerobic glycolysis (the Warburg Effect), and cell signaling. Its properties make it a valuable reagent for investigating cellular stress and HIF1 pathways.
- IUPAC
- 2-[(1-methylpropyl)dithio]-1H-imidazole
- Synonyms
- 2-[(1-methylpropyl)dithio]-1H-imidazole
Cancer Metabolism Research
PX 12 is utilized to investigate the metabolic alterations characteristic of cancer cells, focusing on the Warburg effect and related pathways. It aids in understanding how cancer cells reprogram their metabolism to fuel rapid growth and proliferation.
Cellular Stress and Signaling Studies
This compound serves as a tool for exploring cellular responses to stress, including pathways involving nitric oxide and oxidative stress. It is valuable for researchers studying cell signaling mechanisms and their modulation.
HIF1 Pathway Investigations
PX 12 is employed in research focusing on Hypoxia-Inducible Factor 1 (HIF1) and its role in cellular adaptation to low oxygen conditions. It can be used to study inhibitors and activators within this critical pathway.
| Molecular weight | 188.31 |
|---|---|
| Empirical formula | C7H12N2S2 |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | off-white to tan |
| Solubility | DMSO: >25 mg/mL |
| Storage temperature | 2-8°C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is PX 12 used for?
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PX 12 is primarily used in scientific research for studying cancer metabolism, aerobic glycolysis (the Warburg Effect), cell signaling, cellular stress, and HIF1 pathways.
What is the CAS number and chemical formula for PX 12?
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The CAS number for PX 12 is 141400-58-0, and its empirical formula is C7H12N2S2.
What grade and purity does Tech Serve Solutions supply for PX 12?
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Tech Serve Solutions supplies PX 12 with a purity of ≥98% (HPLC). This product is not supplied as USP, BP, EP, or pharmacopoeia grade and is intended for research purposes.
How should PX 12 be handled safely?
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PX 12 is a Warning substance (GHS07) that can cause skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Always handle in a well-ventilated area, wear appropriate personal protective equipment (gloves, eye protection), and avoid breathing dust. Refer to the Safety Data Sheet for full details.
How is PX 12 packed and shipped?
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PX 12 is typically supplied as an off-white to tan powder and stored at 2-8°C. It is carefully packed and exported by Tech Serve Solutions, adhering to all relevant shipping regulations for research chemicals.
How can I request a quote or sample for PX 12?
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To request a quote or sample of PX 12, please contact the Tech Serve Solutions sales team through our website or via the provided contact information, specifying the product CAS number 141400-58-0.
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