Psammaplin A
Psammaplin A (CAS: 110659-91-1), with the empirical formula C22H24Br2N4O6S2 and a molar mass of 672.32 g/mol, is a potent, non-nucleoside analog inhibitor of DNA methyltransferases. It is supplied as a solid. This compound is widely utilised in biochemical research, particularly for studies involving epigenetics, gene regulation, and cell signalling pathways. Its specific mechanism of action makes it a valuable tool for investigating DNA methylation processes and their impact on cellular function.
- IUPAC
- Bisprasin, N,N\"-(dithiodi-2,1-ethanediyl)bis[3-bromo-4-hydroxy-a-(hydroxyimino)-benzenepropanamide
Epigenetic Research
Psammaplin A serves as a critical reagent for researchers studying DNA methylation and its role in gene expression. It is used to investigate the mechanisms of DNA methyltransferase (DNMT) inhibition and its downstream effects on cellular processes.
Cell Biology Studies
This compound is applied in cell biology to explore the influence of epigenetic modifications on cell growth, differentiation, and response to stimuli. Its ability to inhibit DNMTs offers insights into cellular regulatory networks.
Neuroscience Research
Psammaplin A finds application in neuroscience research to understand the role of DNA methylation in neuronal function and development. It can be used to probe epigenetic mechanisms relevant to neurological conditions.
Drug Discovery and Development
As a well-characterised DNMT inhibitor, Psammaplin A can be used as a research tool in the early stages of drug discovery, particularly in the development of epigenetic therapies.
| Empirical formula | C22H24Br2N4O6S2 |
|---|---|
| Assay | ≥97% (HPLC) |
| Form | solid |
| Solubility | DMSO: >10 mg/mLH2O: insoluble |
| Storage temperature | 2-8°C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Psammaplin A primarily used for?
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Psammaplin A is primarily used as a potent, non-nucleoside analog inhibitor of DNA methyltransferases in research settings, particularly for studies in epigenetics, cell biology, and neuroscience.
What are the CAS number and molecular formula for Psammaplin A?
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The CAS number for Psammaplin A is 110659-91-1, and its empirical formula is C22H24Br2N4O6S2.
What grade and purity does Tech Serve Solutions supply for Psammaplin A?
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Tech Serve Solutions supplies Psammaplin A with an assay of ≥97% (HPLC). We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should Psammaplin A be handled and stored?
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Psammaplin A is a solid that may cause skin, eye, and respiratory irritation (H315-H319-H335). Handle with appropriate personal protective equipment, including a dust mask (type N95), eyeshields, and gloves. Store at 2-8°C.
How is Psammaplin A packed, shipped, and exported?
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Psammaplin A is carefully packed to ensure safe transit and is exported globally by Tech Serve Solutions, adhering to all relevant shipping regulations for chemical compounds.
How can I request a sample or quote for Psammaplin A?
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To request a sample or a quotation for Psammaplin A, please contact our sales team via the website or direct inquiry channels.
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