Protopine hydrochloride
Protopine hydrochloride (CAS 6164-47-2) is a quaternary ammonium alkaloid with the molecular formula C20H19NO5·HCl and a molecular weight of 389.83 g/mol. This compound is classified as a calcium channel modulator and is recognised for its role in cell biology and signaling research. It is primarily utilised as a research chemical to investigate ion channel function and related cellular processes, offering a valuable tool for neuroscientific and pharmacological studies.

Calcium Channel Modulation Research
Protopine hydrochloride is employed as a research tool to study the function and regulation of calcium channels. Its properties as a modulator can help elucidate the physiological roles of these channels in various biological systems.
Cell Biology and Signaling Studies
This alkaloid serves as a valuable reagent in cell biology to investigate cellular signaling pathways. Researchers use it to explore how different signaling cascades are affected by calcium influx or modulation.
Neuroscience Research
As a compound interacting with ion channels, protopine hydrochloride finds application in neuroscience for studying neuronal excitability and synaptic transmission. Its effects on voltage-gated ion channels are of particular interest.
Phytochemical Research
Protopine hydrochloride is a phytochemical that can be used in studies focused on natural products and their biological activities. It contributes to the understanding of plant-derived compounds and their potential pharmacological effects.
| Molecular weight | 389.83 |
|---|---|
| Empirical formula | C20H19NO5·HCl |
| Assay | ≥98% |
| Form | solid |
| Storage temperature | 2-8°C |

Hazard statements
- H301Toxic if swallowed
Precautionary statements
- P301IF SWALLOWED
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25 |
| Safety statements (S) | 36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Protopine hydrochloride used for?
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Protopine hydrochloride is primarily used as a research chemical for studies in cell biology, cell signaling, neuroscience, and as a calcium channel modulator. Its specific applications involve investigating ion channel function and related cellular processes.
What is the CAS number and formula for Protopine hydrochloride?
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The CAS number for Protopine hydrochloride is 6164-47-2, and its molecular formula is C20H19NO5·HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Protopine hydrochloride with an assay of ≥98%. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated in the product specifications.
How should Protopine hydrochloride be handled safely?
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Protopine hydrochloride is classified as Danger with hazard statement H301 (Toxic if swallowed). Recommended personal protective equipment includes eyeshields, faceshields, gloves, and P2 respirator cartridges. Handling should be done with appropriate precautions to avoid ingestion and inhalation.
How is Protopine hydrochloride packaged and shipped?
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Protopine hydrochloride is typically supplied as a solid and is stored at 2-8°C. Shipping is conducted in compliance with relevant regulations for hazardous materials, such as UN 2811.
How can I request a quote or sample for Protopine hydrochloride?
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To request a quote or sample of Protopine hydrochloride, please contact our sales department through the website or by phone. Our team will assist you with your inquiry promptly.
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