β-Propiolactone
β-Propiolactone (CAS 57-57-8, C3H4O2) is a cyclic ester with a molecular weight of 72.06 g/mol. This colourless liquid, also known as 3-hydroxypropionic acid lactone, is a reactive organic building block. It serves as a versatile intermediate in chemical synthesis, particularly in the production of polymers and pharmaceuticals. Its reactivity necessitates careful handling and storage under controlled conditions to maintain its integrity.
- IUPAC
- 3-Hydroxypropionic acid lactone,Hydracrylic acid β-lactone
- Synonyms
- 3-Hydroxypropionic acid lactoneHydracrylic acid β-lactone
Chemical Synthesis Intermediate
β-Propiolactone is employed as a key intermediate in various organic syntheses. It can be used to introduce the propiolactone moiety or to generate reactive species for further functionalization in complex molecule construction.
Polymer Production
This lactone can undergo ring-opening polymerization to form poly(β-propiolactone). While not as common as other polyesters, research explores its potential in creating biodegradable or specialty polymers.
Pharmaceutical Precursor
It serves as a building block in the synthesis of certain pharmaceutical compounds. Its specific structure allows for the introduction of desired functional groups in drug discovery and development processes.
| Molecular weight | 72.06 |
|---|---|
| Empirical formula | C3H4O2 |
| Assay | ≥90% |
| Boiling point | 162 °C(lit.) |
| Density | 1.146 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.412(lit.) |
| Storage temperature | −20°C |
| Melting point | −33 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H330Fatal if inhaled
- H350May cause cancer
Precautionary statements
- P201Obtain special instructions before use
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P284Wear respiratory protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 70 °C / 158 °F |
| Transport (UN / ADR) | UN 3382 6.1 / PGI |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 45-26-36/38 |
| Safety statements (S) | 53-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is β-Propiolactone used for?
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β-Propiolactone is primarily used as an intermediate in chemical synthesis, a precursor in the production of polymers, and a building block for pharmaceuticals.
What are the CAS number and formula for β-Propiolactone?
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The CAS number for β-Propiolactone is 57-57-8, and its molecular formula is C3H4O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies β-Propiolactone with an assay of ≥90%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should β-Propiolactone be handled safely?
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β-Propiolactone is a dangerous substance requiring strict safety protocols. It is classified as acutely toxic if inhaled (H330), causes skin irritation (H315), serious eye irritation (H319), and may cause cancer (H350). Always use appropriate personal protective equipment, including a full-face respirator, chemical-resistant gloves, and eye/face protection, and handle only in a well-ventilated area or fume hood.
How is β-Propiolactone packed and exported?
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β-Propiolactone is packed and exported according to stringent international regulations for hazardous materials, including UN 3382 classification. Please contact us for specific shipping and export details.
How can I request a sample or quote for β-Propiolactone?
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To request a sample or a quote for β-Propiolactone, please contact our sales team directly through our website or by phone. Provide your contact details and the quantity required.
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