β-Naphthoflavone
β-Naphthoflavone (CAS: 6051-87-2, C19H12O2) is an off-white to yellow solid with a molecular weight of 272.30 g/mol. This compound, also known as 5,6-Benzoflavone, is recognised for its role as a potent inducer of cytochrome P450 enzymes, particularly in Phase I metabolic pathways. It is frequently employed in biochemical research for studying drug metabolism, enzyme induction, and as a chemopreventive agent in toxicological studies.
- IUPAC
- 5,6-Benzoflavone,BNF,beta-Naphthoflavone
- Synonyms
- 5,6-Benzoflavone, BNF, beta-Naphthoflavone
Enzyme Induction Studies
β-Naphthoflavone is widely used to induce cytochrome P450 enzymes, facilitating research into drug metabolism and xenobiotic interactions. Its ability to selectively induce certain isoforms aids in understanding enzyme kinetics and metabolic pathways.
Cancer Research
As a chemopreventive agent, β-Naphthoflavone has been investigated for its potential role in modulating carcinogenesis. It serves as a valuable tool in preclinical studies for exploring mechanisms of cancer prevention.
Biochemical Research
This compound is utilised in cell biology and biochemical assays to probe cellular responses and signalling pathways affected by P450 enzyme activity. Its applications extend to toxicological assessments and mechanistic investigations.
Chemical Synthesis Building Block
With its distinct benzoflavone structure, β-Naphthoflavone can serve as a building block in the synthesis of more complex organic molecules and heterocyclic compounds for research purposes.
| Molecular weight | 272.30 |
|---|---|
| Empirical formula | C19H12O2 |
| Colour | off-white to yellow |
| Storage temperature | 2-8°C |
| Melting point | 164-166 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | rat ... Gabra2(29706) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is β-Naphthoflavone used for?
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β-Naphthoflavone is primarily used in biochemical and toxicological research as an inducer of cytochrome P450 enzymes, a chemopreventive agent, and a tool for studying drug metabolism and cellular responses.
What is the CAS number and molecular formula for β-Naphthoflavone?
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The CAS number for β-Naphthoflavone is 6051-87-2, and its molecular formula is C19H12O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies β-Naphthoflavone with a specified purity. Please refer to the product specifications or contact us for lot-specific details. We do not represent this product as USP, BP, or EP grade.
How should β-Naphthoflavone be handled safely?
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β-Naphthoflavone is classified as harmful if swallowed (H302). Safe handling requires wearing a dust mask type N95 (US), eyeshields, faceshields, and gloves. Ensure adequate ventilation and avoid dust formation.
How is β-Naphthoflavone packed and shipped?
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β-Naphthoflavone is typically stored at 2-8°C. Tech Serve Solutions professionally packs and exports chemicals globally, adhering to all relevant shipping regulations.
How can I request a quote or sample for β-Naphthoflavone?
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To request a quote or sample for β-Naphthoflavone, please contact the Tech Serve Solutions sales team through our website or by phone.
Is β-Naphthoflavone a controlled substance?
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The provided data does not indicate that β-Naphthoflavone is a controlled substance.
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