WY-14643
WY-14643 (CAS: 50892-23-4), a synthetic compound with the chemical formula C14H14ClN3O2S and a molecular weight of 323.80 g/mol, is recognized for its biological activity. It functions as a potent PPAR agonist, primarily impacting gene regulation. This chemical is a valuable tool in research settings, particularly within cell biology and gene expression studies.
- IUPAC
- 4-Chloro-6-(2,3-xylidino)-2-pyrimidinylthioacetic acid,Pirinixic acid
- Synonyms
- Pirinixic acid4-Chloro-6-(2,3-xylidino)-2-pyrimidinylthioacetic acid

PPAR Agonist Research
WY-14643 acts as a specific agonist for Peroxisome Proliferator-Activated Receptors (PPARs), including PPARA, PPARD, and PPARG in humans. It is utilised in studies investigating the roles of these receptors in metabolic regulation and gene expression.
Cell Biology and Gene Expression
Researchers employ WY-14643 to probe cellular pathways influenced by PPAR activation. Its application aids in understanding gene regulation mechanisms and cellular responses in various biological contexts.
Cell Signaling Investigations
The compound is instrumental in exploring cell signaling cascades modulated by PPARs, contributing to the understanding of cellular communication and responses in neuroscience and related fields.
| Molecular weight | 323.80 |
|---|---|
| Empirical formula | C14H14ClN3O2S |


Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H350May cause cancer
Precautionary statements
- P201Obtain special instructions before use
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
- P308IF exposed or concerned
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 45-22-36/37/38 |
| Safety statements (S) | 53-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... PPARA(5465), PPARD(5467), PPARG(5468)mouse ... Ppara(19013)rat ... Ppara(25747) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is WY-14643 used for?
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WY-14643 is primarily used as a research tool, acting as a potent agonist for Peroxisome Proliferator-Activated Receptors (PPARs). It is employed in studies related to cell biology, gene regulation, and cell signaling.
What is the CAS number and formula for WY-14643?
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The CAS number for WY-14643 is 50892-23-4, and its empirical formula is C14H14ClN3O2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies WY-14643 for research purposes. Specific purity and grade information are available upon request; we do not represent this product as USP, BP, or EP grade.
How should WY-14643 be handled safely?
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WY-14643 is classified as hazardous (Danger). It is harmful if swallowed, causes skin irritation, causes serious eye irritation, and may cause respiratory irritation. It is also suspected of causing cancer. Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection (e.g., N100 respirator), must be used. Handle only in well-ventilated areas and follow all safety precautions, including avoiding exposure and seeking medical attention if necessary.
Is WY-14643 a controlled substance?
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The provided data does not indicate that WY-14643 is a controlled substance.
How is WY-14643 packed, shipped, and exported?
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Tech Serve Solutions, as a specialist global supplier and exporter, ensures appropriate packaging and handling for international shipment of chemicals like WY-14643, adhering to all relevant regulations.
How can I request a sample or quote for WY-14643?
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To request a sample or a quote for WY-14643, please contact the Tech Serve Solutions sales team through the designated channels on our website.
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