Withaferin A
Withaferin A (CAS: 5119-48-2, C28H38O6) is a biologically active compound with a molecular weight of 470.60 g/mol. It is a steroidal lactone isolated from the plant *Withania somnifera*. Withaferin A is recognised for its involvement in cellular processes and is a subject of study in various biological research areas, including cancer research and cell biology, where its effects on cellular signalling and inflammation are investigated.
- IUPAC
- 5,6-Epoxy-4,27-dihydroxy-1-oxowitha-2,24-dienolide,Withaferine A
- Synonyms
- 5,6-Epoxy-4,27-dihydroxy-1-oxowitha-2,24-dienolide
Cancer Research
Withaferin A is utilised in cancer research to investigate its potential anti-cancer properties and mechanisms of action. Its effects on cell proliferation and apoptosis are subjects of ongoing scientific inquiry.
Cell Biology Studies
This compound serves as a tool in cell biology for examining cellular pathways and responses. For example, it has been used to treat cells to study its impact on inflammation in conditions like cystic fibrosis.
Angiogenesis Research
As an angiogenesis inhibitor, Withaferin A is employed in research to understand the processes of new blood vessel formation, a critical aspect in both normal physiology and disease states such as cancer.
| Molecular weight | 470.60 |
|---|---|
| Empirical formula | C28H38O6 |
| Assay | ≥95% (HPLC) |
| Storage temperature | 2-8°C |
| Application | Withaferin A was used to treat HEK293 cells to study its effect on cystic fibrosis inflammation.1 |
| Melting point | 252-253 °C |
| Flash point | 226 °C / 438.8 °F |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Withaferin A used for?
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Withaferin A is used in scientific research, particularly in areas such as cancer research, cell biology, and angiogenesis studies. It has been employed to investigate its effects on cellular inflammation and proliferation.
What are the CAS number and formula for Withaferin A?
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The CAS number for Withaferin A is 5119-48-2, and its empirical formula is C28H38O6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Withaferin A with a purity of ≥95% (HPLC). We do not represent this product as meeting pharmacopoeial standards (e.g., USP, BP, EP).
How should Withaferin A be handled and stored?
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Withaferin A should be handled with appropriate safety precautions. It is classified under WGK Germany 3. The compound is combustible with a flash point of 226 °C (438.8 °F) and has a melting point of 252-253 °C. Recommended storage is at 2-8°C.
Is Withaferin A a scheduled or controlled substance?
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The provided data does not indicate that Withaferin A is a scheduled or controlled substance.
How can I request a sample or quote for Withaferin A?
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To request a sample or quote for Withaferin A, please contact our sales team through the website or by phone. Our team will assist you with your inquiry.
How is Withaferin A packed, shipped, and exported?
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Withaferin A is carefully packed to ensure stability during transit and is available for global export. Specific packaging details can be provided upon request.
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