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O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate

CAS 125700-67-6N′Chemical Synthesis

O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate (CAS: 125700-67-6) is a uronium salt with the molecular formula C11H16N5O · BF4 and a molecular weight of 321.08. This compound serves as an efficient coupling reagent, particularly well-suited for solid-phase peptide synthesis. Its reliability and effectiveness make it a valuable reagent in chemical synthesis and peptide chemistry laboratories.

IUPAC
N,N,N′,N′-Tetramethyl-O-(benzotriazol-1-yl)uronium tetrafluoroborate,TBTU
Synonyms
N′-tetramethyluronium tetrafluoroborate125700-67-6C11H16N5O · BF4TBTU
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O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate (N′) — chemical structure, CAS 125700-67-6; Chemistry, fine chemical supplied by Tech Serve Solutions
Chemical BiologyChemical SynthesisCouplingPeptide ChemistryPeptide CouplingSynthetic Reagents More...
01 /Applications

Solid-Phase Peptide Synthesis

This uronium salt is ideally suited for solid-phase peptide synthesis, facilitating the formation of amide bonds between amino acids.

Chemical Synthesis

As a versatile coupling reagent, it is employed in various chemical synthesis applications where amide bond formation is required.

Peptide Chemistry

It is a key reagent in peptide chemistry, aiding in the construction of peptide chains for research and development.

02 /Properties
Molecular weight321.08
Linear formulaC11H16N5O · BF4
Assay97%
ApplicationCoupling reagent which is ideally suited for solid-phase peptide synthesis.
Melting point205 °C (dec.)(lit.)
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
Protective equipmentdust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)3
Hazard codes (EU)Xi
Risk statements (R)36/37/38
Safety statements (S)26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
125700-67-6
MDL number
MFCD00077413
PubChem substance
24864035
Beilstein registry
7066325
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate used for?

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O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate is primarily used as a coupling reagent, especially for solid-phase peptide synthesis and other chemical synthesis requiring amide bond formation.

What are the CAS number and formula for this compound?

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The CAS number is 125700-67-6, and the linear formula is C11H16N5O · BF4.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies this product with an assay of 97%. We do not represent it as USP, BP, or EP grade.

How should O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate be handled safely?

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This compound is a Warning substance (GHS07) that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). It should be handled with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, in a well-ventilated area.

How is this chemical packed, shipped, and exported?

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Tech Serve Solutions packs, ships, and exports fine chemicals globally, adhering to all necessary regulations for safe transport.

How can I request a sample or quote for this product?

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To request a sample or a quote, please contact the Tech Serve Solutions sales team via our website or direct contact details.

Need O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate in a specific grade or volume?