Potassium benzofuran-2-trifluoroborate
Potassium benzofuran-2-trifluoroborate (CAS: 929626-27-7) is an organoboron compound with the formula C8H5BF3KO and a molecular weight of 224.03 g/mol. This trifluoroborate salt serves as a valuable reagent in organic synthesis, particularly in cross-coupling reactions. Its structure, featuring a benzofuran core and a trifluoroborate group, enables the formation of carbon-carbon bonds, making it useful in the preparation of complex organic molecules and pharmaceutical intermediates.
- IUPAC
- Potassium 2-benzofuranyltrifluoroborate,Potassium benzofuranyl-2-trifluoroborate
Suzuki-Miyaura Cross-Coupling Reactions
Potassium benzofuran-2-trifluoroborate is employed as a coupling partner in Suzuki-Miyaura reactions, facilitating the efficient synthesis of biaryl and heteroaryl compounds. It reacts with aryl or vinyl halides under palladium catalysis to form new carbon-carbon bonds.
Synthesis of Heterocyclic Compounds
This reagent is instrumental in constructing complex heterocyclic frameworks, including substituted benzofurans, which are common structural motifs in pharmaceuticals and agrochemicals. Its trifluoroborate moiety offers stability and controlled reactivity.
Medicinal Chemistry and Drug Discovery
In medicinal chemistry, Potassium benzofuran-2-trifluoroborate can be used to introduce the benzofuran scaffold into potential drug candidates. This is valuable for exploring structure-activity relationships and developing novel therapeutic agents.
Materials Science
The benzofuran unit is present in various functional materials; this trifluoroborate derivative can be utilised in the synthesis of novel organic materials with specific electronic or optical properties.
| Molecular weight | 224.03 |
|---|---|
| Empirical formula | C8H5BF3KO |
| Assay | 90% |
| Melting point | 310-353 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Potassium benzofuran-2-trifluoroborate used for?
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Potassium benzofuran-2-trifluoroborate is primarily used as a reagent in organic synthesis, particularly in palladium-catalysed cross-coupling reactions like the Suzuki-Miyaura coupling, for the formation of carbon-carbon bonds and the synthesis of complex heterocyclic compounds.
What is the CAS number and formula for Potassium benzofuran-2-trifluoroborate?
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The CAS number for Potassium benzofuran-2-trifluoroborate is 929626-27-7, and its empirical formula is C8H5BF3KO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Potassium benzofuran-2-trifluoroborate with an assay of 90%. We do not represent this product as meeting USP, BP, EP, or other pharmacopoeial standards.
What are the main safety hazards associated with this chemical?
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This compound is a Warning substance and may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment in a well-ventilated area.
How is Potassium benzofuran-2-trifluoroborate typically packed and shipped?
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This chemical is typically packed securely in appropriate containers for safe handling, storage, and international export, adhering to all relevant shipping regulations for chemical substances.
How can I request a quote or a sample?
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To request a quote or a sample, please contact our sales team directly through our website or by calling our customer service line. Provide the product name and CAS number for efficient processing.
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