Polyoxyethylene bis(azide)
Polyoxyethylene bis(azide) (CAS 82055-94-5) is a versatile homobifunctional polyethylene glycol derivative featuring azide end groups. This compound is a valuable reagent in chemical biology and synthesis, particularly for conjugation applications. Its ability to react with alkynes via click chemistry makes it instrumental in bioconjugation, materials science, and polymer chemistry. The compound exhibits a transition temperature (Tm) between 29-35 °C and is supplied by TSS for research and development purposes.
- IUPAC
- O,O′-Bis(2-azidoethyl)polyethylene glycol,PEG-diazide
- Synonyms
- O,O′-Bis(2-azidoethyl)polyethylene glycolPEG-diazide
Bioconjugation Chemistry
Polyoxyethylene bis(azide) serves as a key reagent for conjugating biomolecules. Its terminal azide groups readily participate in copper-catalyzed or strain-promoted azide-alkyne cycloaddition (CuAAC or SPAAC) reactions, enabling the attachment of proteins, peptides, or nucleic acids to various surfaces or other molecules.
Materials Science
In materials science, this compound is used to functionalise surfaces and create novel polymer architectures. The polyethylene glycol backbone offers desirable properties such as hydrophilicity and biocompatibility, while the azide termini allow for precise modifications and crosslinking.
Polymer Synthesis
Polyoxyethylene bis(azide) acts as a building block for synthesizing advanced polymeric materials. It can be incorporated into polymer chains or used to create crosslinked polymer networks, enabling tailored material properties for diverse applications.
Chemical Biology Tools
This azide-functionalised PEG derivative is employed in the development of chemical biology tools, facilitating the study of biological processes. Its use in click chemistry allows for the non-invasive labelling and detection of biomolecules within complex biological systems.
| Storage temperature | 2-8°C |
|---|---|
| Melting point | 55-60 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Transition Temp | Tm 29-35 °C |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Polyoxyethylene bis(azide) used for?
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Polyoxyethylene bis(azide) is primarily used in bioconjugation, materials science, polymer synthesis, and as a tool in chemical biology due to its azide end groups which enable click chemistry reactions.
What is the CAS number and formula for Polyoxyethylene bis(azide)?
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The CAS number for Polyoxyethylene bis(azide) is 82055-94-5. The chemical formula is not provided in the product data.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Polyoxyethylene bis(azide) for research and development. The specific assay or purity is not detailed in the provided data, and TSS does not represent this product as USP, BP, or EP grade.
What are the safety and handling considerations for Polyoxyethylene bis(azide)?
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When handling Polyoxyethylene bis(azide), it is essential to use appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound is classified under WGK Germany 3.
How is Polyoxyethylene bis(azide) shipped and exported?
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Polyoxyethylene bis(azide) requires storage at 2-8°C. TSS can facilitate worldwide export of this chemical to meet your research and industrial needs.
How can I request a sample or quote for Polyoxyethylene bis(azide)?
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To request a sample or a quote for Polyoxyethylene bis(azide), please contact the Tech Serve Solutions sales team through our website or by phone.
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