Poly(ethylene glycol) methyl ether tosylate
Poly(ethylene glycol) methyl ether tosylate (CAS: 58320-73-3) is a monofunctional derivative of polyethylene glycol with the linear formula CH3O(CH2CH2O)nCH2CH2OSO2C6H4CH3. It presents an average number-average molecular weight (Mn) of 900 g/mol and a low polydispersity index (Mw/Mn < 1.1). This versatile reagent is widely employed in polymer science and materials science for various chemical syntheses and surface modifications.
- IUPAC
- Methoxy PEG tosylate,Methoxypolyethylene glycol tosylate,PEG tosylate,mPEG tosylate
- Synonyms
- Methoxy PEG tosylateMethoxypolyethylene glycol tosylatePEG tosylatemPEG tosylate

Polymer Synthesis
Poly(ethylene glycol) methyl ether tosylate serves as a valuable building block in the synthesis of advanced polymers. Its tosylate group acts as an excellent leaving group, facilitating controlled polymerization reactions and the creation of functionalized polymer chains.
Surface Modification
This compound is utilised for modifying surfaces, imparting desirable properties such as biocompatibility or altered hydrophilicity. It enables the covalent attachment of PEG chains to various substrates, crucial in biomaterials and nanotechnology.
Organic Synthesis
In organic synthesis, the tosylate functionality allows for nucleophilic substitution reactions. This enables the introduction of the methoxy-PEG moiety into diverse organic molecules, creating complex structures for research purposes.
| Linear formula | CH3O(CH2CH2O)nCH2CH2OSO2C6H4CH3 |
|---|---|
| Form | solid or liquid |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Flash point | >110 °C / >230 °F |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Mol Wt | average Mn 900 |
|---|---|
| Mw Mn | <1.1 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Poly(ethylene glycol) methyl ether tosylate used for?
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Poly(ethylene glycol) methyl ether tosylate is primarily used in polymer synthesis, surface modification, and general organic synthesis. It acts as a key reagent for introducing PEG chains and functionalizing various materials and molecules.
What is the CAS number and formula for Poly(ethylene glycol) methyl ether tosylate?
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The CAS number is 58320-73-3 and the linear formula is CH3O(CH2CH2O)nCH2CH2OSO2C6H4CH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Poly(ethylene glycol) methyl ether tosylate with an average Mn of 900 g/mol and a polydispersity index (Mw/Mn) of less than 1.1. This is typically supplied as a technical or research grade material, and TSS does not represent it as USP, BP, or EP grade.
How should Poly(ethylene glycol) methyl ether tosylate be handled safely?
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Poly(ethylene glycol) methyl ether tosylate is a Warning substance that may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, ensuring adequate ventilation, and avoid breathing dust/fume/gas/mist/vapours/spray. In case of contact with eyes, rinse cautiously with water for several minutes and remove contact lenses if present and easy to do. Continue rinsing.
Is this chemical available for international export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals and laboratory reagents, including Poly(ethylene glycol) methyl ether tosylate.
How can I request a sample or quote?
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Please contact our sales team via the website or directly to request a sample or a formal quotation for Poly(ethylene glycol) methyl ether tosylate.
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