PK 11195
PK 11195 (CAS: 85532-75-8), with the molecular formula C21H21ClN2O and a molecular weight of 352.86 g/mol, is a chemical compound primarily recognised for its role in neuroscientific research. As a selective sigma-1 receptor antagonist, it is instrumental in investigating various neurological pathways and functions. Its specific biochemical activity makes it a valuable tool for understanding receptor interactions within the central nervous system.
- IUPAC
- 1-(2-Chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide
Neuroscience Research
PK 11195 serves as a key pharmacological tool for researchers studying the sigma-1 receptor and its involvement in central nervous system functions. It is used to investigate receptor binding, signal transduction, and potential therapeutic targets.
Pharmacological Studies
This compound aids in the characterisation of sigma-1 receptors and their influence on various physiological processes. Its selective antagonism provides insights into the role of these receptors in conditions such as pain, anxiety, and neurodegenerative disorders.
Biochemical Assays
PK 11195 is utilised in in vitro and in vivo assays to determine receptor occupancy, drug-receptor interactions, and the downstream effects of sigma-1 receptor modulation.
| Molecular weight | 352.86 |
|---|---|
| Empirical formula | C21H21ClN2O |
| Gene Information | human ... BZRAP1(9256), TSPO(706)rat ... Gabra2(29706), Tspo(24230) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is PK 11195 used for?
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PK 11195 is primarily used in neuroscience and pharmacological research as a selective antagonist for the sigma-1 receptor, aiding in the study of neurological pathways and receptor functions.
What is the CAS number and chemical formula for PK 11195?
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The CAS number for PK 11195 is 85532-75-8, and its chemical formula is C21H21ClN2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies PK 11195 as a research-grade chemical. The specific assay and purity are detailed in the product's Certificate of Analysis. TSS does not represent this product as USP, BP, EP, or pharmacopoeia grade.
What are the safety considerations for handling PK 11195?
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PK 11195 is classified with a WGK Germany rating of 3, indicating a high degree of hazard to water. Appropriate personal protective equipment should be used, and handling should occur in a well-ventilated area, following standard laboratory safety protocols to avoid exposure.
How is PK 11195 packed, shipped, and exported?
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Tech Serve Solutions offers secure and compliant packing for PK 11195, suitable for domestic and international shipment. As a global supplier, TSS adheres to all relevant shipping and export regulations for chemical compounds.
How can I request a sample or quote for PK 11195?
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To request a sample or a quote for PK 11195, please contact the Tech Serve Solutions sales team through our website or by phone, providing your contact details and the quantity required.
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