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Piperidine-4-boronic acid pinacol ester hydrochloride

CAS 1218790-99-8C11H22BNO2 ⋅ HClChemical Synthesis

Piperidine-4-boronic acid pinacol ester hydrochloride (CAS: 1218790-99-8) is an organoboron compound with the formula C11H22BNO2 ⋅ HCl. Supplied as a reagent with an assay of 95%, it is primarily used in organic synthesis, particularly for the construction of carbon-carbon bonds via Suzuki-Miyaura cross-coupling reactions. This compound serves as a valuable building block for creating more complex molecules in research and development settings, especially within medicinal chemistry and materials science.

IUPAC
4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine hydrochloride
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Piperidine-4-boronic acid pinacol ester hydrochloride (C11H22BNO2 ⋅ HCl) — chemical structure, CAS 1218790-99-8; Chemistry, fine chemical supplied by Tech Serve Solutions
Boronate EstersChemical SynthesisHeteroaryl Boronate EstersOrganometallic Reagents
01 /Applications

Suzuki-Miyaura Cross-Coupling

This pinacol boronate ester is a key reagent in Suzuki-Miyaura cross-coupling reactions, enabling the formation of C-C bonds by coupling with aryl or vinyl halides/triflates. It is instrumental in synthesising complex organic structures.

Medicinal Chemistry

Its piperidine core and boronic ester functionality make it a useful intermediate in the synthesis of pharmacologically active compounds. It aids in the development of novel drug candidates.

Materials Science

This compound can be employed in the synthesis of novel organic materials, contributing to the development of functional polymers and electronic components through controlled chemical synthesis.

Chemical Synthesis Building Block

As a versatile organometallic reagent, it functions as a valuable building block for constructing diverse molecular architectures in advanced organic chemistry research.

02 /Properties
Empirical formulaC11H22BNO2 ⋅ HCl
Assay95%
Storage temperature2-8°C
Melting point188-192 °C
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H302Harmful if swallowed
Water hazard class (WGK, DE)3
Hazard codes (EU)Xn
Risk statements (R)22

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
1218790-99-8
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Piperidine-4-boronic acid pinacol ester hydrochloride used for?

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Piperidine-4-boronic acid pinacol ester hydrochloride (CAS: 1218790-99-8) is primarily used as a building block in organic synthesis, notably for Suzuki-Miyaura cross-coupling reactions, and in the development of medicinal chemistry and materials science compounds.

What are the CAS number and formula for this compound?

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The CAS number is 1218790-99-8, and the empirical formula (Hill notation) is C11H22BNO2 ⋅ HCl.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies this product with an assay of 95%. This is typically considered a technical or research grade suitable for general laboratory use. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.

How should Piperidine-4-boronic acid pinacol ester hydrochloride be handled?

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This compound is classified as harmful if swallowed (H302) and requires careful handling. Store at 2-8°C and use appropriate personal protective equipment, including gloves, eye protection, and protective clothing, to avoid ingestion or contact. Refer to the Safety Data Sheet (SDS) for comprehensive handling guidelines.

Is this compound a controlled substance?

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The provided data does not indicate that Piperidine-4-boronic acid pinacol ester hydrochloride is a controlled substance. However, users should always verify local regulations.

How is this product shipped and exported?

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Tech Serve Solutions specialises in the global supply and export of fine chemicals, including this product. Packaging and shipping comply with international regulations for chemical transport.

How can I request a sample or quote?

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To request a sample or a quote for Piperidine-4-boronic acid pinacol ester hydrochloride, please contact the Tech Serve Solutions sales team through our website or by phone.

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