Pindolol
Pindolol (CAS: 13523-86-9; Formula: C14H20N2O2; MW: 248.32 g/mol) is a white to off-white powder. As a non-selective beta-adrenergic receptor antagonist with intrinsic sympathomimetic activity, it functions primarily in cardiovascular and neurological research. Pindolol is a valuable tool for studying adrenergic receptor pathways and is utilised in the development of new therapeutic agents for conditions affecting the cardiovascular and central nervous systems.
- IUPAC
- 1-(1H-Indol-4-yloxy)-3-(isopropylamino)-2-propanol,1-(1H-Indol-4-yloxy)-3-[(1-methylethyl)amino]-2-propanol
- Synonyms
- 1-(1H-Indol-4-yloxy)-3-(isopropylamino)-2-propanol1-(1H-Indol-4-yloxy)-3-[(1-methylethyl)amino]-2-propanol
Cardiovascular Research
Pindolol serves as a pharmacological tool in the study of beta-adrenergic receptor function and its role in regulating blood pressure and heart rate. Its intrinsic sympathomimetic activity allows for nuanced investigation into receptor signalling pathways.
Neuroscience Research
This compound is employed in research focused on neurotransmission and the function of adrenergic and serotonergic receptors in the central nervous system. It aids in understanding the mechanisms underlying mood regulation and neurological disorders.
Drug Discovery and Development
Pindolol is utilised as a reference compound and intermediate in the discovery and development of novel therapeutic agents targeting adrenergic and other related receptor systems. Its known pharmacological profile aids in lead optimisation and efficacy studies.
| Molecular weight | 248.32 |
|---|---|
| Empirical formula | C14H20N2O2 |
| Assay | ≥98% (TLC) |
| Form | powder |
| Colour | white to off-white |
| Solubility | 0.1 M NaOH: soluble0.2 mg/mL45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble0.2 mg/mL0.1 M HCl: soluble20 mg/mLH2O: insoluble |
| Storage temperature | 2-8°C |
| Melting point | 167-171 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... ADRB1(153), HTR1A(3350) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Pindolol used for?
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Pindolol is used in research for studying adrenergic receptor pathways, cardiovascular function, and neuroscience, and as a reference compound in drug discovery.
What are the CAS number and chemical formula for Pindolol?
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The CAS number for Pindolol is 13523-86-9, and its chemical formula is C14H20N2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Pindolol with an assay of ≥98% (TLC). This product is intended for research and laboratory use and is not represented as USP, BP, or EP grade.
How should Pindolol be handled safely?
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Pindolol is a Warning substance (GHS07) and is harmful if swallowed, causes skin irritation, causes serious eye irritation, and may cause respiratory irritation (H302-H315-H319-H335). Handle with appropriate personal protective equipment including a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation.
How is Pindolol typically packed and shipped?
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Pindolol is typically supplied as a powder and is stored at 2-8°C. TSS exports chemicals globally, adhering to all relevant shipping regulations.
How can I request a sample or quote for Pindolol?
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To request a sample or a quote for Pindolol, please contact our sales team via the website or by phone with your specific requirements.
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