Pimaricin

CAS 7681-93-8C33H47NO13Biochemicals & Reagents

Pimaricin (CAS: 7681-93-8, C33H47NO13) is an amphoteric macrolide antifungal antibiotic produced by Streptomyces chattanoogensis. This compound functions by binding to ergosterol and cholesterol, thereby disrupting cell membrane permeability. It is primarily utilised topically for fungal infections and as a fungicide in laboratory agar media. Pimaricin also serves as a valuable tool in biochemical research for studying lipid bilayer dynamics and regulatory systems in microorganisms.

IUPAC: Natamycin
Synonyms: Natamycin

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Pimaricin (C33H47NO13) — chemical structure, CAS 7681-93-8; Life Science, fine chemical supplied by Tech Serve Solutions

Analytical StandardsAnalytical/ChromatographyAntibioticsAntibiotics A to ZAntibiotics N-SAntifungalBiochemicals and ReagentsChemical Structure ClassChromatographyEnvironmental Standards

01 /Applications

Antifungal Agent

Pimaricin is employed topically for the treatment of various fungal infections. Its mechanism involves targeting ergosterol in fungal cell membranes, leading to disruption of cellular integrity.

Fungicide in Culture Media

As a fungicide, Pimaricin is added to agar media to prevent the overgrowth of fungi, ensuring the selective isolation and study of bacteria or other desired microorganisms in laboratory settings.

Biochemical Research Tool

This compound serves as an ergosterol and cholesterol binding agent, facilitating research into lipid bilayer dynamics, particularly within fungal cells. It is also used to investigate regulatory systems in Streptomyces.

02 /Properties

Molecular weight	665.73
Empirical formula	C33H47NO13
Assay	≥95% (HPLC)
Density	1.0 g/mL at 20 °C(lit.)
Concentration	~2.5%
Storage temperature	2-8°C
Application	Pimaricin is an amphoteric macrolide antifungal antibiotic from Streptomyces chattanoogensis. It is used for a variety of fungal infections, mainly topically. It is used as a ergosterol and cholesterol binding agent to study lipid bilayer dynamics, especially in fungal cells. Pimaricin is used as a fungicide in agar media. It is used to study the pleitropic regulator AdpAch 1 and the gamma-butyrolactone regulatory system of Streptomyces chattanoogensis2.
Biological source	from Streptomyces chattanoogensis

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

7681-93-8

MDL number

MFCD00135085

PubChem substance

24899055

05 /Additional specifications

Quality Level	PREMIUM
Sterility	γ-irradiated

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Pimaricin used for?

Pimaricin is used as a topical antifungal agent for various fungal infections and as a fungicide in laboratory agar media. It is also utilized in biochemical research to study lipid bilayer dynamics and microbial regulatory systems.

What are the CAS number and formula for Pimaricin?

The CAS number for Pimaricin is 7681-93-8 and its molecular formula is C33H47NO13.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Pimaricin at a PREMIUM quality level with an assay of ≥95% by HPLC. We do not represent this product as USP, BP, or EP grade.

How should Pimaricin be handled safely?

When handling Pimaricin, it is essential to use appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is also recommended. Dispose of in accordance with local regulations.

How is Pimaricin shipped and exported by TSS?

Pimaricin is gamma-irradiated and shipped under refrigerated conditions (2-8°C). Tech Serve Solutions is experienced in global export of fine chemicals and laboratory reagents.