Phenylsulfur pentafluoride
Phenylsulfur pentafluoride (CAS: 2557-81-5; Formula: C6H5F5S) is an organic compound with a molecular weight of 204.16. As a fluorinated building block, it serves as a valuable intermediate in organic synthesis, particularly for introducing sulfur-fluorine functionalities. Its properties make it useful in research and development for creating novel molecules with potential applications in various chemical sectors.
- IUPAC
- Pentafluoro(phenyl)sulfur

Organic Synthesis Intermediate
Phenylsulfur pentafluoride is employed as a building block in the synthesis of complex organic molecules. It facilitates the introduction of the pentafluorosulfanyl group (-SF5) into various chemical structures.
Fluorinated Compound Development
This compound is utilized in the development of new fluorinated organic materials. The unique properties imparted by the -SF5 group can lead to enhanced chemical stability and altered electronic characteristics in target molecules.
Research and Development
Researchers in academic and industrial settings use Phenylsulfur pentafluoride for exploring novel chemical reactions and designing new compounds with tailored properties for diverse applications.
| Molecular weight | 204.16 |
|---|---|
| Empirical formula | C6H5F5S |
| Density | 1.496 g/mL at 25 °C |
| Refractive index | n20/D 1.435 |


Hazard statements
- H226Flammable liquid and vapour
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 43 °C / 109.4 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 10-22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Phenylsulfur pentafluoride used for?
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Phenylsulfur pentafluoride is primarily used as a building block in organic synthesis for introducing the pentafluorosulfanyl group (-SF5) into molecules and in the development of novel fluorinated organic compounds for research purposes.
What are the CAS number and formula for Phenylsulfur pentafluoride?
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The CAS number for Phenylsulfur pentafluoride is 2557-81-5, and its empirical formula is C6H5F5S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Phenylsulfur pentafluoride typically as a technical or research grade chemical. We do not represent this product as meeting USP, BP, or EP pharmacopoeia standards.
How should Phenylsulfur pentafluoride be handled safely?
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Phenylsulfur pentafluoride is a flammable liquid and vapour (H226), harmful if swallowed (H302), causes skin irritation (H315), causes serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields, face shields, gloves, and suitable respiratory protection, should be used. Handle in a well-ventilated area and keep away from heat and ignition sources.
How is Phenylsulfur pentafluoride packed and exported?
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Phenylsulfur pentafluoride is packed in accordance with UN 1993 C3 / PGIII regulations for safe transportation. Tech Serve Solutions is experienced in exporting chemicals globally.
How can I request a sample or quote for Phenylsulfur pentafluoride?
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To request a sample or a quote for Phenylsulfur pentafluoride, please contact our sales team through the website or by phone.
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