Phenylzinc bromide solution
Phenylzinc bromide solution (CAS 38111-44-3), with the linear formula C<sub>6</sub>H<sub>5</sub>ZnBr and a molecular weight of 222.40 g/mol, is a valuable organozinc reagent supplied by Tech Serve Solutions. This compound is primarily utilised in organic synthesis, particularly in cross-coupling reactions. Its reactivity makes it a key intermediate for forming carbon-carbon bonds in the synthesis of complex organic molecules and active pharmaceutical ingredients.
Organozinc Reagent in Cross-Coupling
Phenylzinc bromide solution serves as a crucial organozinc reagent in various palladium-catalysed cross-coupling reactions, such as Negishi couplings, enabling the formation of new carbon-carbon bonds.
Synthesis of Biologically Active Molecules
It is employed in the construction of complex organic structures, including intermediates for pharmaceuticals and agrochemicals, where precise functionalisation of aromatic rings is required.
Intermediate for Fine Chemicals
The compound facilitates the introduction of phenyl groups into diverse molecular frameworks, supporting the synthesis of fine chemicals and advanced materials.
| Molecular weight | 222.40 |
|---|---|
| Linear formula | C6H5ZnBr |
| Boiling point | 65 °C |
| Density | 0.99 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | -17 °C / 1.4 °F |
| Transport (UN / ADR) | UN 3399 4.3/PG 2 |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-14-19-34-37 |
| Safety statements (S) | 16-26-36/37/39-45 |
| Supplemental hazards | May form explosive peroxides., Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Phenylzinc bromide solution used for?
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Phenylzinc bromide solution is primarily used in organic synthesis as an organozinc reagent for cross-coupling reactions, facilitating the formation of carbon-carbon bonds in the synthesis of complex organic molecules and pharmaceutical intermediates.
What is the CAS number and formula for Phenylzinc bromide solution?
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The CAS number for Phenylzinc bromide solution is 38111-44-3, and its linear formula is C<sub>6</sub>H<sub>5</sub>ZnBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Phenylzinc bromide solution at a concentration of 0.5 M in THF. TSS does not represent this product as USP, BP, or EP grade; it is intended for research and technical applications.
How should Phenylzinc bromide solution be handled safely?
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Phenylzinc bromide solution is flammable and reacts violently with water, and it can cause severe skin burns and eye damage. It may also cause respiratory irritation. Handle with extreme caution in a well-ventilated area, wearing appropriate personal protective equipment including gloves, eye protection, and respiratory protection. Avoid contact with water and ignition sources.
How is Phenylzinc bromide solution packed and shipped?
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Phenylzinc bromide solution is typically packed in suitable containers for air transport and shipped according to relevant dangerous goods regulations (UN 3399 4.3/PG 2). Storage at 2-8°C is recommended.
How can I request a sample or quote for Phenylzinc bromide solution?
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To request a sample or quote for Phenylzinc bromide solution, please contact the Tech Serve Solutions sales team through our website or by phone.
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