4-Chlorophenoxyacetyl chloride
4-Chlorophenoxyacetyl chloride (CAS: 4122-68-3) is an organic compound with the molecular formula C₈H₆Cl₂O₂ and a molecular weight of 205.04 g/mol. As an acid halide and carbonyl compound, it serves as a valuable building block in organic synthesis. This chemical is primarily utilized in the preparation of various organic intermediates and complex molecules, contributing to advancements in chemical research and development.
Preparation of Substituted Acetophenone Derivatives
4-Chlorophenoxyacetyl chloride is employed in synthetic routes leading to substituted acetophenone derivatives. These compounds can serve as intermediates in the development of pharmaceuticals and fine chemicals.
Synthesis of Quinuclidine Derivatives
This acid chloride is a key reagent in the synthesis of complex heterocyclic structures, such as 2-(4-chlorophenoxyacetylamino)-3-ethoxycarbonyl[2,3-b]quinuclidine. Such molecules are of interest in medicinal chemistry research.
Formation of Acetohydrazide Derivatives
The compound facilitates the formation of substituted acetohydrazides, including 2-(4-chlorophenoxy)-N′-[2-(4-chlorophenoxy)acetyl]acetohydrazide monohydrate. These reactions are integral to creating novel organic compounds.
| Molecular weight | 205.04 |
|---|---|
| Linear formula | ClC6H4OCH2COCl |
| Assay | 98% |
| Boiling point | 142 °C/17 mmHg(lit.) |
| Density | 1.314 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5486(lit.) |
| Application | 4-Chlorophenoxyacetyl chloride was used in the preparation of:• substituted acetophenone derivatives1• 2-(4-chlorophenoxyacetylamino)-3-ethoxycarbonyl[2,3-b]quinuclidine2• 2-(4-chlorophenoxy)-N′-[2-(4-chlorophenoxy)acetyl]acetohydrazide monohydrate3 |
| Melting point | 18.8 °C(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 23-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Chlorophenoxyacetyl chloride used for?
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4-Chlorophenoxyacetyl chloride is primarily used as a building block in organic synthesis for the preparation of substituted acetophenone derivatives, quinuclidine derivatives, and acetohydrazide derivatives.
What is the CAS number and formula for 4-Chlorophenoxyacetyl chloride?
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The CAS number for 4-Chlorophenoxyacetyl chloride is 4122-68-3, and its linear formula is C₈H₆Cl₂O₂.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Chlorophenoxyacetyl chloride with an assay of 98%. This is a technical grade for research and synthesis purposes and is not represented as USP, BP, or EP grade.
How should 4-Chlorophenoxyacetyl chloride be handled safely?
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4-Chlorophenoxyacetyl chloride is a corrosive substance (H314) that causes severe skin burns and eye damage. Handle with appropriate personal protective equipment, including a full-face respirator, chemical-resistant gloves, and goggles. Ensure adequate ventilation and immediate access to eyewash stations and safety showers.
Is this product controlled or scheduled?
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The provided data does not indicate that 4-Chlorophenoxyacetyl chloride is a controlled or scheduled substance.
How is 4-Chlorophenoxyacetyl chloride packed and exported?
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4-Chlorophenoxyacetyl chloride is packed and shipped according to international regulations for hazardous materials, including UN 3265, Class 8, Packing Group II. TSS is experienced in global export.
How can I request a quote or sample?
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To request a quote or sample of 4-Chlorophenoxyacetyl chloride, please contact our sales team through the website or by phone, providing your specific requirements.
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