Phenylbutazone
Phenylbutazone (CAS: 50-33-9), a pyrazolidinedione derivative with the molecular formula C19H20N2O2 and a molecular weight of 308.37 g/mol, is a potent anti-inflammatory agent. It functions by inhibiting cyclooxygenase (COX) enzymes, thereby reducing prostaglandin synthesis. This compound is primarily utilised in research settings to study inflammation pathways and its effects on cyclooxygenase enzymes, particularly COX-1 and COX-2. Tech Serve Solutions supplies Phenylbutazone for laboratory and research purposes.
- IUPAC
- 4-Butyl-1,2-diphenyl-3,5-pyrazolidinedione

Research into Inflammatory Pathways
Phenylbutazone serves as a valuable tool in biochemical research to investigate the mechanisms of inflammation. Its known inhibitory effect on cyclooxygenase enzymes allows researchers to study the role of prostaglandins in various biological processes.
Cyclooxygenase (COX) Enzyme Studies
This compound is employed to explore the function and inhibition of cyclooxygenase enzymes (COX-1 and COX-2). Understanding these enzymes is crucial for research into pain and inflammation management.
Biochemical Reagent
As a well-characterized molecule, Phenylbutazone is used as a reagent in cell biology and related fields for experimental studies. It helps in understanding cellular responses and signaling cascades.
| Molecular weight | 308.37 |
|---|---|
| Empirical formula | C19H20N2O2 |
| Melting point | 106-108 °C(lit.) |

Hazard statements
- H301Toxic if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... CYP2C9(1559), PTGIS(5740), PTGS2(5743) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Phenylbutazone used for?
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Phenylbutazone is primarily used in laboratory research to study inflammation pathways and as an inhibitor of cyclooxygenase (COX) enzymes. It is not intended for human or animal consumption.
What are the CAS number and molecular formula for Phenylbutazone?
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The CAS number for Phenylbutazone is 50-33-9, and its molecular formula is C19H20N2O2.
What grade and purity does Tech Serve Solutions supply for Phenylbutazone?
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Tech Serve Solutions supplies Phenylbutazone as a technical/research grade chemical. We do not represent it as USP, BP, or EP grade.
How should Phenylbutazone be handled safely?
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Phenylbutazone is hazardous. Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, faceshields, and gloves. Avoid inhalation of dust and ensure adequate ventilation. Refer to the Safety Data Sheet for detailed handling instructions.
Is Phenylbutazone a controlled substance?
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The provided data does not indicate that Phenylbutazone is a controlled substance.
How is Phenylbutazone packed, shipped, and exported?
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Phenylbutazone is packed and shipped according to relevant regulations for hazardous materials. As a global supplier, Tech Serve Solutions has experience in exporting chemicals worldwide.
How can I request a sample or quote for Phenylbutazone?
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To request a sample or quote for Phenylbutazone, please contact our sales team through the website or by phone. Provide the product name and CAS number.
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