Phenoxazine
Phenoxazine (CAS: 135-67-1; C12H9NO; MW: 183.21) is a tricyclic compound utilised as a building block in chemical synthesis. It functions as a 2′deoxycytidine analog, enhancing cellular uptake and improving stacking interactions between heterocycles in oligonucleotide/RNA hybrids. Phenoxazine is purified by sublimation to achieve a high assay of ≥99%. Tech Serve Solutions supplies this versatile chemical for research and development applications.
Oligonucleotide and RNA Hybridisation
Phenoxazine serves as a 2′deoxycytidine analog, promoting improved stacking interactions between heterocyclic bases in oligonucleotide/RNA hybrids. This enhances the stability and binding affinity of nucleic acid structures.
Enhanced Cellular Uptake
The unique structure of Phenoxazine facilitates increased cellular uptake of modified nucleic acids. This is crucial for the delivery of therapeutic oligonucleotides and RNA molecules into cells.
Heterocyclic Building Block
As a heterocyclic building block, Phenoxazine is a valuable intermediate in the synthesis of complex organic molecules. Its structure allows for further functionalisation in diverse chemical pathways.
| Molecular weight | 183.21 |
|---|---|
| Empirical formula | C12H9NO |
| Assay | ≥99% |
| Solubility | benzene: freely soluble(lit.)chloroform: freely soluble(lit.)diethyl ether: freely soluble(lit.)ethanol: freely soluble(lit.)petroleum ether: very slightly soluble(lit.) |
| Application | Phenoxazine is a tricyclic 2′deoxycytidine analog that has been used to improve stacking interactions between heterocycles of oligonucleotide/RNA hybrids and to enhance cellular uptake1. |
| Melting point | 156-159 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Purified By | sublimation |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Phenoxazine used for?
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Phenoxazine is used as a 2′deoxycytidine analog to enhance cellular uptake and improve stacking interactions in oligonucleotide/RNA hybrids. It also serves as a heterocyclic building block in chemical synthesis.
What is the CAS number and formula for Phenoxazine?
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The CAS number for Phenoxazine is 135-67-1, and its empirical formula is C12H9NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Phenoxazine with a purity of ≥99%, purified by sublimation. We do not represent this product as USP, BP, EP, or other pharmacopoeial grades.
What are the safety precautions for handling Phenoxazine?
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When handling Phenoxazine, it is essential to wear eyeshields and gloves. A respirator filter of type N95 (US) or P1 (EN143) is recommended. Ensure adequate ventilation.
Is Phenoxazine a controlled substance?
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The provided data does not indicate that Phenoxazine is a controlled substance.
How is Phenoxazine packed, shipped, and exported?
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Phenoxazine is carefully packed to ensure safe transit and is available for export globally by Tech Serve Solutions.
How can I request a sample or quote for Phenoxazine?
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To request a sample or quote for Phenoxazine, please contact our sales team through the website or by phone.
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