Pentafluorophenylhydrazine
Pentafluorophenylhydrazine (CAS 828-73-9), with the molecular formula C6F5NHNH2 and a molecular weight of 198.09 g/mol, is a fluorinated organic building block. This compound serves as a valuable reagent in chemical synthesis. Its primary application involves its use in analytical chemistry, specifically in determining the purity of other compounds, such as N-tert-butyl-N-[1-diethylphosphono-(2,2-dimethylpropyl)]nitroxide (DEPN) via 1H NMR spectroscopy. Tech Serve Solutions supplies this chemical with an assay of 97%.
- IUPAC
- (Perfluorophenyl)hydrazine,NSC 88334,PFPH
- Synonyms
- (Perfluorophenyl)hydrazinePFPH

Purity Determination in Analytical Chemistry
Pentafluorophenylhydrazine has been employed as a reagent in 1H NMR spectroscopy to ascertain the purity of other chemical compounds. For instance, it has been used in the precise determination of N-tert-butyl-N-[1-diethylphosphono-(2,2-dimethylpropyl)]nitroxide (DEPN) purity.
Fluorinated Organic Synthesis
As a key aryl fluorinated building block, pentafluorophenylhydrazine is utilised in various organic synthesis pathways. Its unique fluorinated structure allows for the introduction of pentafluorophenyl groups into target molecules, facilitating the creation of novel compounds with specific properties.
Research and Development
This compound serves as a versatile intermediate in research laboratories exploring new synthetic methodologies and developing novel chemical entities. Its reactivity profile makes it a useful starting material for a range of chemical transformations.
| Molecular weight | 198.09 |
|---|---|
| Linear formula | C6F5NHNH2 |
| Assay | 97% |
| Application | The product has been used to determine the purity of N-tert-butyl-N-[1-diethylphosphono-(2,2-dimethylpropyl)]nitroxide (DEPN) using 1H NMR spectroscopy.1 |
| Melting point | 74-76 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Pentafluorophenylhydrazine used for?
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Pentafluorophenylhydrazine (CAS 828-73-9) is primarily used in chemical synthesis as a fluorinated organic building block and in analytical chemistry for determining the purity of other compounds, such as DEPN, via 1H NMR spectroscopy.
What are the CAS number and molecular formula for Pentafluorophenylhydrazine?
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The CAS number for Pentafluorophenylhydrazine is 828-73-9, and its linear formula is C6F5NHNH2.
What grade and purity does Tech Serve Solutions supply for Pentafluorophenylhydrazine?
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Tech Serve Solutions supplies Pentafluorophenylhydrazine with a purity of 97%. This product is not represented as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling considerations for Pentafluorophenylhydrazine?
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Pentafluorophenylhydrazine is classified with a Warning signal word, with hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including eyeshields, gloves, and a dust mask (N95 type), should be used. Handle in a well-ventilated area and avoid breathing dust.
How is Pentafluorophenylhydrazine packed, shipped, and exported by TSS?
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Tech Serve Solutions, a global supplier and exporter, ensures appropriate packaging for Pentafluorophenylhydrazine to maintain its integrity during domestic and international shipments, adhering to all relevant regulations for hazardous materials.
How can I request a quote or sample of Pentafluorophenylhydrazine?
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To request a quote or sample of Pentafluorophenylhydrazine, please contact the TSS sales team through our website or direct contact information, providing your specific requirements.
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