PD-156707
PD-156707 (CAS: 162412-70-6), a sodium salt with the empirical formula C28H25O9·Na, is a potent endothelin receptor antagonist. This bioactive small molecule is primarily utilised in research settings as a valuable tool for studying cell signaling pathways, particularly those involving endothelin. Its application extends to neuroscience research and the investigation of cardiovascular conditions, serving as a key reagent for exploring receptor-ligand interactions and their physiological consequences.
- IUPAC
- α-[2-(4-Methoxyphenyl)-2-oxo-1-[(3,4,5-trimethoxyphenyl)methyl]ethylidene]-1,3-benzodioxole-5-acetic acid sodium salt
Endothelin Receptor Antagonism Research
PD-156707 acts as a selective antagonist of endothelin receptors, making it invaluable for in vitro and in vivo studies investigating the physiological roles of endothelin peptides. It aids in understanding pathways related to vasoconstriction and cell proliferation.
Cardiovascular Research Tool
This compound is employed in research focused on cardiovascular diseases where endothelin signaling plays a critical role. It helps researchers explore potential therapeutic targets and mechanisms underlying conditions such as pulmonary hypertension.
Cell Signaling and Neuroscience Studies
As a modulator of GPCRs, PD-156707 is used to probe cell signaling cascades and their impact on neuronal function. Its application in neuroscience research aids in understanding complex biological processes.
| Empirical formula | C28H25O9·Na |
|---|---|
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to off-white |
| Solubility | DMSO: ≥20 mg/mL |
| Storage temperature | room temp |
Hazard statements
- H410Very toxic to aquatic life with long-lasting effects
Precautionary statements
- P273Avoid release to the environment
- P501Dispose of contents and container per local regulations
| Transport (UN / ADR) | UN 3077 9 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | N |
| Risk statements (R) | 50/53 |
| Safety statements (S) | 60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is PD-156707 used for?
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PD-156707 is primarily used as a research chemical, specifically as an endothelin receptor antagonist, for studying cell signaling, cardiovascular conditions, and neuroscience.
What are the CAS number and formula for PD-156707?
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The CAS number for PD-156707 is 162412-70-6, and its empirical formula is C28H25O9·Na.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies PD-156707 with an assay of ≥98% by HPLC. This is a research-grade chemical and is not represented as USP, BP, EP, or any pharmacopoeial standard.
How should PD-156707 be handled safely?
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PD-156707 is classified as GHS09 with the signal word Warning, and carries the hazard statement H410 (Very toxic to aquatic life with long lasting effects). Handle with appropriate personal protective equipment in a well-ventilated area, and avoid release into the environment. Follow precautionary statements P273 and P501.
How is PD-156707 packaged and shipped?
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PD-156707 is supplied as a white to off-white powder. It is packaged appropriately for safe transport and is exported globally by Tech Serve Solutions.
How can I request a sample or quote for PD-156707?
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To request a sample or a quote for PD-156707, please contact the Tech Serve Solutions sales team through our website or by phone.
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