PIPES sesquisodium salt
PIPES sesquisodium salt (CAS 100037-69-2) is a zwitterionic organic chemical compound with the formula C8H16.5N2Na1.5O6S2. Its molecular weight is 335.34 g/mol. As a biological buffer, PIPES is characterised by its pKa of 6.8, making it effective within a useful pH range of 6.1–7.5. This makes it suitable for various biochemical and biological applications where stable pH control is critical.
- IUPAC
- 1,4-Piperazinediethanesulfonic acid sesquisodium salt,Piperazine-1,4-bis(2-ethanesulfonic acid) sesquisodium salt

Biological Buffering Agent
PIPES sesquisodium salt functions as a biological buffer, maintaining stable pH in experimental systems. Its pKa of 6.8 is well-suited for physiological conditions and various enzymatic assays. It is widely used in molecular biology, cell culture, and protein chemistry.
Diagnostic Assay Manufacturing
This compound is utilised in the manufacturing of diagnostic assays, where precise pH control is essential for the reliability and accuracy of test results. Its zwitterionic nature contributes to minimal interference with biological reactions.
Biochemical Research
PIPES sesquisodium salt serves as a crucial reagent in biochemical research. It facilitates the study of biological molecules and processes by providing a consistent pH environment for experiments.
| Molecular weight | 335.34 |
|---|---|
| Empirical formula | C8H16.5N2Na1.5O6S2 |
| Assay | ≥99% (titration) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Pka 25 °C | 6.8 |
|---|---|
| Market Segment | Diagnostic Assay Manufacturing |
| Useful Ph Range | 6.1 - 7.5 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is PIPES sesquisodium salt used for?
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PIPES sesquisodium salt is primarily used as a biological buffer in research and diagnostic applications, maintaining stable pH in the range of 6.1–7.5, with a pKa of 6.8.
What are the CAS number and formula for PIPES sesquisodium salt?
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The CAS number for PIPES sesquisodium salt is 100037-69-2, and its empirical formula is C8H16.5N2Na1.5O6S2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies PIPES sesquisodium salt with an assay of ≥99% (titration). We do not represent this product as USP, BP, or EP grade.
How should PIPES sesquisodium salt be handled safely?
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When handling PIPES sesquisodium salt, it is essential to use personal protective equipment including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if necessary. The compound has a WGK rating of 3 in Germany, indicating a higher hazard.
How is PIPES sesquisodium salt packed, shipped, and exported?
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PIPES sesquisodium salt is carefully packed to ensure stability during transit. Tech Serve Solutions is a global supplier and exporter, experienced in shipping chemicals worldwide in compliance with international regulations.
How can I request a sample or quote for PIPES sesquisodium salt?
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To request a sample or a quote for PIPES sesquisodium salt, please contact our sales team through the website or by phone. We are happy to assist with your specific requirements.
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