o-Tolyl isothiocyanate
o-Tolyl isothiocyanate (CAS 614-69-7), chemical formula CH3C6H4NCS, is a key organic building block and sulfur compound. With a molecular weight of 149.21 g/mol, this isothiocyanate derivative is primarily utilised in chemical synthesis and research laboratories. Its reactive nature makes it valuable for introducing the isothiocyanate functional group into more complex molecules, facilitating diverse organic transformations and the development of novel chemical entities.
Organic Synthesis Intermediate
o-Tolyl isothiocyanate serves as a versatile intermediate in the synthesis of various organic compounds, including heterocyclic structures and pharmaceuticals. Its isothiocyanate group readily participates in nucleophilic addition reactions, enabling the construction of complex molecular frameworks.
Research and Development
This compound is frequently employed in academic and industrial research settings for exploring new synthetic pathways and developing novel materials. It aids in the creation of custom molecules and the investigation of structure-activity relationships.
Reagent in Organic Chemistry
As a sulfur-containing organic building block, o-Tolyl isothiocyanate is used as a reagent for specific chemical transformations. It is particularly useful for reactions involving nitrogen and sulfur heterocycles.
| Molecular weight | 149.21 |
|---|---|
| Linear formula | CH3C6H4NCS |
| Assay | 99% |
| Boiling point | 239 °C(lit.) |
| Density | 1.115 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.6361(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 108 °C / 226.4 °F |
| Transport (UN / ADR) | UN 2810 6.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is o-Tolyl isothiocyanate used for?
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o-Tolyl isothiocyanate (CAS 614-69-7) is primarily used as an intermediate in organic synthesis and for research and development purposes in chemical laboratories. It is a sulfur compound valuable for introducing the isothiocyanate functional group into other molecules.
What are the CAS number and chemical formula for o-Tolyl isothiocyanate?
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The CAS number for o-Tolyl isothiocyanate is 614-69-7, and its chemical formula is CH3C6H4NCS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies o-Tolyl isothiocyanate with a minimum assay of 99%. This product is suitable for research and chemical synthesis; TSS does not represent it as USP, BP, EP, or any other pharmacopoeia grade.
How should o-Tolyl isothiocyanate be handled safely?
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o-Tolyl isothiocyanate is classified with GHS07 symbol and a Warning signal word. It is harmful if swallowed, in contact with skin, and if inhaled, and causes skin and eye irritation, and may cause respiratory irritation (H302-H312-H315-H319-H332-H335). Always use appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, and handle in a well-ventilated area or fume hood.
Can Tech Serve Solutions export o-Tolyl isothiocyanate?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including o-Tolyl isothiocyanate, adhering to all relevant shipping regulations.
How can I request a sample or quote for o-Tolyl isothiocyanate?
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To request a sample or a quote for o-Tolyl isothiocyanate, please contact our sales department through the website or by phone, providing your specific requirements and shipping details.
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