o-Tolyl isocyanate
o-Tolyl isocyanate (CAS: 614-68-6, CH3C6H4NCO) is a key organic building block with a molecular weight of 133.15. This compound is primarily utilised in chemical synthesis for the formation of various derivatives. Its reactive isocyanate group makes it a valuable intermediate in the production of pharmaceuticals and other complex organic molecules. Tech Serve Solutions supplies this compound for research and industrial applications.
- IUPAC
- 2-Methylphenyl isocyanate
Organic Synthesis Intermediate
o-Tolyl isocyanate serves as a versatile intermediate in organic synthesis. Its electrophilic isocyanate functional group readily reacts with nucleophiles, enabling the construction of diverse molecular structures.
Pharmaceutical Precursor
This compound can be employed in the multi-step synthesis of pharmaceutical active ingredients and related compounds. Its incorporation into larger molecules is a common strategy in drug discovery and development.
Research and Development
Utilised in academic and industrial R&D settings, o-Tolyl isocyanate facilitates the exploration of new chemical reactions and the creation of novel materials and compounds.
| Molecular weight | 133.15 |
|---|---|
| Linear formula | CH3C6H4NCO |
| Assay | ≥99% |
| Boiling point | 185 °C(lit.) |
| Density | 1.074 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.535(lit.) |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H334May cause allergy or asthma symptoms if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P342
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 92 °C / 197.6 °F |
| Transport (UN / ADR) | UN 3334 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38-42 |
| Safety statements (S) | 23-26-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is o-Tolyl isocyanate used for?
+
o-Tolyl isocyanate is primarily used as an intermediate in organic synthesis, particularly in the development and production of pharmaceuticals and other complex organic molecules.
What are the CAS number and formula for o-Tolyl isocyanate?
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The CAS number for o-Tolyl isocyanate is 614-68-6, and its molecular formula is CH3C6H4NCO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies o-Tolyl isocyanate with an assay of ≥99%. TSS does not represent this product as USP, BP, EP or other pharmacopoeia grades.
How is o-Tolyl isocyanate safely handled?
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o-Tolyl isocyanate is a Danger substance, harmful if swallowed, in contact with skin or if inhaled (H302 + H312 + H332). It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335) and allergy or asthma symptoms or breathing difficulties if inhaled (H334). Ensure adequate ventilation, wear appropriate personal protective equipment including gloves, eyeshields, and a suitable respirator.
How is o-Tolyl isocyanate packed and shipped?
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o-Tolyl isocyanate is packed according to safety regulations for hazardous materials. It is available for domestic and international export.
How can I request a quote or sample of o-Tolyl isocyanate?
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To request a quote or sample of o-Tolyl isocyanate, please contact our sales team through our website or by phone.
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