o-Toluoyl chloride
o-Toluoyl chloride (CAS: 933-88-0), with the molecular formula CH₃C₆H₄COCl and a molecular weight of 154.59 g/mol, is an organic acid halide. It serves as a valuable intermediate and building block in various chemical syntheses. This compound is primarily utilised in organic chemistry research and industrial applications for the introduction of the o-toluoyl group into other molecules.
- IUPAC
- 2-Methylbenzoyl chloride
- Synonyms
- 2-Methylbenzoyl chlorideo-Tolyl chloride2-Toluic acid chloride
Organic Synthesis Intermediate
o-Toluoyl chloride is a key reagent in organic synthesis, enabling the formation of esters, amides, and ketones. Its reactivity allows for its use in the preparation of more complex organic molecules.
Pharmaceutical Precursor
This compound can be employed as a building block in the synthesis of active pharmaceutical ingredients (APIs) and related intermediates. Its specific structural features are often incorporated into drug candidates.
Chemical Research Reagent
Utilised in academic and industrial research laboratories, o-Toluoyl chloride facilitates the exploration of new chemical reactions and the development of novel compounds. It is a standard reagent for acylations.
| Molecular weight | 154.59 |
|---|---|
| Linear formula | CH3C6H4COCl |
| Assay | 99% |
| Boiling point | 88-90 °C/12 mmHg(lit.) |
| Density | 1.185 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5549(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 77 °C / 170.6 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34-36/37 |
| Safety statements (S) | 23-26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is o-Toluoyl chloride used for?
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o-Toluoyl chloride is primarily used as an intermediate and building block in organic synthesis, including the preparation of pharmaceuticals and other complex organic molecules.
What is the CAS number and chemical formula for o-Toluoyl chloride?
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The CAS number for o-Toluoyl chloride is 933-88-0, and its linear formula is CH₃C₆H₄COCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions typically supplies o-Toluoyl chloride with an assay of 99%. We do not represent this product as meeting USP, BP, or EP pharmacopoeia standards.
How should o-Toluoyl chloride be handled?
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o-Toluoyl chloride is corrosive and may cause severe skin burns and eye damage, and can irritate the respiratory tract. Handle with appropriate personal protective equipment, including gloves, eye protection, and respiratory protection. Ensure adequate ventilation.
Is o-Toluoyl chloride a controlled substance?
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Based on the provided data, o-Toluoyl chloride is not listed as a controlled or scheduled substance.
How is o-Toluoyl chloride packed and exported?
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o-Toluoyl chloride is shipped and exported in compliance with relevant regulations for hazardous materials, such as UN 3265, Class 8, Packing Group II.
How can I request a quote or sample of o-Toluoyl chloride?
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Please contact our sales department directly via our website or by phone to request a quotation or a sample of o-Toluoyl chloride.
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