o-Phenylene phosphorochloridate

CAS 1499-17-8C6H4ClO3PCatalysis & Inorganic

o-Phenylene phosphorochloridate (CAS: 1499-17-8), with the molecular formula C6H4ClO3P and a molecular weight of 190.52 g/mol, is a crucial chemical intermediate. This compound serves as a versatile phosphorylation agent and a key reactant in the synthesis of various complex organic molecules. Its applications span the preparation of biologically relevant compounds, such as uridine diphosphate-glucose derivatives with potential antifungal activity, and novel vinyloxy phosphorus monomers.

IUPAC: 2-Chloro-1,3,2-benzodioxaphosphole 2-oxide,o-Phenylene chlorophosphate,Catechol cyclophosphorochloridate

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o-Phenylene phosphorochloridate (C6H4ClO3P) — chemical structure, CAS 1499-17-8; Chemistry, fine chemical supplied by Tech Serve Solutions

Chemical SynthesisPhosphine CompoundsPhosphorus Precursors

01 /Applications

Synthesis of Uridine Diphosphate-Glucose Derivatives

Utilised as a reactant for the preparation of uridine diphosphate-glucose derivatives. These compounds are investigated for their potential to act as chain terminators in β-glucan biosynthesis and exhibit antifungal properties.

Preparation of Vinyloxy Phosphorus Monomers

Serves as a precursor in the synthesis of vinyloxy phosphorus monomers. These monomers can be employed in the development of novel polymeric materials with specific properties.

General Phosphorylation Agent

Functions as an effective phosphorylation agent in organic synthesis. This capability allows for the introduction of phosphate groups into various organic molecules, facilitating further chemical transformations.

02 /Properties

Molecular weight	190.52
Empirical formula	C6H4ClO3P
Grade	technical grade
Boiling point	120 °C/9 mmHg(lit.)
Application	Reactant for preparation of: • Uridine diphosphate-glucose derivatives as potential chain terminators of β-glucan biosynthesis with antifungal activity1• Vinyloxy phosphorus monomers2• Phosphorylation agent3

03 /Safety & handling

GHS hazard pictogram: Corrosive (GHS05) — Corrosive

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves, clothing and eye/face protection
P305IF IN EYES
P310Immediately call a POISON CENTER or doctor

Protective equipment	Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Transport (UN / ADR)	UN 3261 8 / PGII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	C
Risk statements (R)	14-34
Safety statements (S)	26-36/37/39-45
Supplemental hazards	Reacts violently with water.

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

1499-17-8

MDL number

MFCD00005854

PubChem substance

24849594

Beilstein registry

142368

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is o-Phenylene phosphorochloridate used for?

o-Phenylene phosphorochloridate is used as a reactant for the preparation of uridine diphosphate-glucose derivatives with potential antifungal activity and vinyloxy phosphorus monomers. It also serves as a general phosphorylation agent in chemical synthesis.

What is the CAS number and chemical formula for o-Phenylene phosphorochloridate?

The CAS number is 1499-17-8 and the chemical formula is C6H4ClO3P.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies o-Phenylene phosphorochloridate in technical grade. We do not represent this product as USP, BP, or EP grade.

How should o-Phenylene phosphorochloridate be handled safely?

o-Phenylene phosphorochloridate is corrosive and reacts violently with water (H314). Handle with extreme care using appropriate personal protective equipment, including eyeshields, face shields, gloves, and suitable respiratory protection. Avoid contact with water. Refer to the Safety Data Sheet for detailed handling instructions.

How is o-Phenylene phosphorochloridate packed and shipped?

As a global supplier and exporter, Tech Serve Solutions ensures appropriate packaging and shipment in accordance with international regulations for hazardous materials. Specific details regarding UN 3261, Class 8, Packing Group II apply.

How can I request a quote or sample for o-Phenylene phosphorochloridate?

To request a quote or a sample of o-Phenylene phosphorochloridate, please contact our sales team through the TSS website or by calling our customer service line.