O-(2-Azidoethyl)heptaethylene glycol
O-(2-Azidoethyl)heptaethylene glycol (CAS: 352439-36-2, Formula: C16H33N3O8) is a heterobifunctional polyethylene glycol derivative, featuring an azide group at one end and a hydroxyl group at the other. This structure makes it an invaluable building block in chemical synthesis and materials science. It is widely employed in bioconjugation chemistry, enabling precise linking of molecules via click chemistry reactions, and in surface modification to introduce specific functionalities.
- IUPAC
- Azido-PEG (n=7)

Bioconjugation Chemistry
This azide-functionalized PEG serves as a versatile linker in bioconjugation, allowing for the precise attachment of biomolecules to surfaces or other molecules through click chemistry, such as the copper-catalyzed azide-alkyne cycloaddition (CuAAC).
Materials Science
It is used in materials science for surface modification and the development of functionalized materials. The PEG chain provides hydrophilicity and biocompatibility, while the terminal azide group offers a reactive handle for further chemical functionalization.
Drug Delivery Systems
The compound can be incorporated into drug delivery systems to improve solubility, stability, and targeted delivery of therapeutic agents due to the properties conferred by the polyethylene glycol backbone.
Chemical Synthesis
As a heterobifunctional building block, it facilitates the synthesis of complex molecular architectures and polymers with specific end-group functionalities.
| Molecular weight | 395.45 |
|---|---|
| Empirical formula | C16H33N3O8 |
| Assay | ≥95% (oligomer purity) |
| Storage temperature | 2-8°C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Mol Wt | average Mn 400 |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is O-(2-Azidoethyl)heptaethylene glycol used for?
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O-(2-Azidoethyl)heptaethylene glycol is primarily used in bioconjugation chemistry for linking molecules, in materials science for surface modification, and as a building block in chemical synthesis, particularly for creating drug delivery systems.
What are the CAS number and formula for O-(2-Azidoethyl)heptaethylene glycol?
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The CAS number is 352439-36-2, and the empirical formula is C16H33N3O8.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies O-(2-Azidoethyl)heptaethylene glycol with an assay of ≥95% oligomer purity. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should O-(2-Azidoethyl)heptaethylene glycol be handled safely?
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This compound is classified as a Warning. It can cause skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). It is recommended to wear eyeshields, gloves, and a dust mask type N95 (US). Ensure good ventilation and avoid breathing dust. In case of contact with eyes, rinse cautiously with water for several minutes (P305 + P351 + P338) and consult a physician if irritation persists (P261).
How is O-(2-Azidoethyl)heptaethylene glycol shipped?
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O-(2-Azidoethyl)heptaethylene glycol is typically stored at 2-8°C and is available for export globally by Tech Serve Solutions.
How can I request a quote or sample?
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To request a quote or a sample of O-(2-Azidoethyl)heptaethylene glycol, please contact our sales department through the website or by telephone.
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