O-(2-Azidoethyl)-O′-methyl-triethylene glycol
O-(2-Azidoethyl)-O′-methyl-triethylene glycol (CAS: 606130-90-9) is an organic compound with the formula C9H19N3O4 and a molecular weight of 233.26 g/mol. This functionalized oligoethylene glycol features an azide group, making it a valuable building block in chemical synthesis and materials science. It is commonly employed in conjugation chemistry, particularly in click chemistry reactions involving alkynes, and in PEGylation applications.
- IUPAC
- 1-{2-[2-(2-Azidoethoxy)ethoxy]ethoxy}-2-methoxyethane,13-Azido-2,5,8,11-tetraoxatridecane

Chemical Synthesis Building Block
Utilised as a versatile intermediate in organic synthesis, its azide functionality allows for facile incorporation into more complex molecular structures. The oligoethylene glycol chain imparts desirable solubility and pharmacokinetic properties.
Conjugation Chemistry
This compound is instrumental in bioconjugation and materials functionalisation via click chemistry, reacting efficiently with alkynes to form stable triazole linkages. It is a key reagent for applications in chemical biology and medicinal chemistry.
PEGylation Reagent
The oligoethylene glycol backbone makes it suitable for PEGylation strategies, which aim to improve the properties of biomolecules or surfaces by attaching polyethylene glycol chains. This can enhance solubility, reduce immunogenicity, and prolong circulation times.
Materials Science
Its unique structure enables the modification of materials surfaces and the synthesis of novel polymers or functionalised nanoparticles. The azide group provides a reactive handle for further chemical transformations.
| Molecular weight | 233.26 |
|---|---|
| Empirical formula | C9H19N3O4 |
| Assay | ≥90% (NMR) |
| Storage temperature | 2-8°C |

Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Mol Wt | average Mn 200 |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is O-(2-Azidoethyl)-O′-methyl-triethylene glycol used for?
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O-(2-Azidoethyl)-O′-methyl-triethylene glycol is primarily used as a building block in chemical synthesis, particularly in conjugation chemistry (e.g., click reactions) and PEGylation applications. It is also employed in materials science and chemical biology research.
What are the CAS number and formula for O-(2-Azidoethyl)-O′-methyl-triethylene glycol?
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The CAS number for O-(2-Azidoethyl)-O′-methyl-triethylene glycol is 606130-90-9, and its molecular formula is C9H19N3O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies O-(2-Azidoethyl)-O′-methyl-triethylene glycol with an assay of ≥90% (NMR). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should O-(2-Azidoethyl)-O′-methyl-triethylene glycol be handled safely?
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This compound is harmful if swallowed (H302). When handling, wear appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Ensure adequate ventilation and avoid ingestion.
How is O-(2-Azidoethyl)-O′-methyl-triethylene glycol packed, shipped, and exported?
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Tech Serve Solutions packs and ships this chemical in accordance with all relevant regulations to ensure safe transit. We are a global supplier and exporter of fine chemicals.
How can I request a sample or quote for O-(2-Azidoethyl)-O′-methyl-triethylene glycol?
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To request a sample or a quote, please contact our sales team through the website or by phone. Provide the product name or CAS number (606130-90-9) for prompt service.
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