Nocodazole
Nocodazole (CAS: 31430-18-9, Formula: C14H11N3O3S, Molar Mass: 301.32 g/mol) is a white powder supplied by TSS. This compound is recognised for its biological activity and is primarily utilised in research settings. Its key applications revolve around its properties as an antitumor agent and a tool for investigating cellular processes, particularly those involving microtubules.
- IUPAC
- Methyl N-(5-thenoyl-2-benzimidazolyl)carbamate,Methyl [5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]carbamate,Oncodazole,R 17934,[5-(2-Thienylcarbonyl)-1H-benzimidazol-2-yl]-carbamic acid methyl ester
- Synonyms
- Methyl N-(5-thenoyl-2-benzimidazolyl)carbamateMethyl [5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]carbamateOncodazoleR 17934[5-(2-Thienylcarbonyl)-1H-benzimidazol-2-yl]-carbamic acid methyl ester
Antitumor Research
Nocodazole serves as a valuable agent in preclinical research for understanding and developing antitumor therapies. It is used to investigate mechanisms of cancer cell growth inhibition and to explore potential drug candidates.
Cell Biology Studies
This compound is widely employed in cell biology to study the dynamics of microtubules. Researchers use Nocodazole to investigate cell division, cell structure, and intracellular transport processes dependent on the cytoskeleton.
Microtubule Inhibition
As a potent microtubule inhibitor, Nocodazole is instrumental in experimental research focused on the cytoskeleton. It helps elucidate the role of microtubules in various cellular functions and disease states.
| Molecular weight | 301.32 |
|---|---|
| Empirical formula | C14H11N3O3S |
| Assay | ≥99% (TLC) |
| Form | powder |
| Colour | white |
| Solubility | DMSO: soluble10 mg/mL (may require heating)H2O: insoluble |
| Storage temperature | 2-8°C |
| Melting point | 300 °C (dec.) |
Hazard statements
- H341Suspected of causing genetic defects
- H361D
Precautionary statements
- P281Use personal protective equipment as required
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 63-68 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Quality Level | PREMIUM |
|---|---|
| Gene Information | human ... TUBB(203068) |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Nocodazole used for?
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Nocodazole (CAS: 31430-18-9) is primarily used in research as an antitumor agent and for studying cell biology, particularly microtubule dynamics.
What are the CAS number and formula for Nocodazole?
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The CAS number for Nocodazole is 31430-18-9, and its empirical formula is C14H11N3O3S.
What grade and purity does Tech Serve Solutions supply for Nocodazole?
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Tech Serve Solutions supplies Nocodazole with an assay of ≥99% (TLC) and a quality level of PREMIUM. We do not represent this product as USP, BP, or EP grade.
How should Nocodazole be handled and stored?
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Nocodazole is classified with GHS08 symbol and 'Warning' signal word, carrying hazard statements H341 (Suspected of causing genetic defects) and H361d (Suspected of damaging the unborn child). It requires handling with eyeshields, gloves, and an appropriate respirator filter (type N95 or P1). Store at 2-8°C.
Is Nocodazole a controlled substance?
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The provided data does not indicate that Nocodazole is a controlled substance.
How is Nocodazole packed and shipped?
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Nocodazole is supplied as a white powder. Specific packaging and shipping details for export are available upon request.
How can I request a quote or sample of Nocodazole?
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To request a quote or sample of Nocodazole, please contact our sales team through the website or your dedicated account manager.
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