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[Nle11]-Substance P

CAS 57462-42-7C64H100N18O13Cell Biology

[Nle11]-Substance P (CAS: 57462-42-7) is a synthetic peptide analogue of Substance P, with the molecular formula C64H100N18O13 and a molecular weight of 1329.59 g/mol. It functions as a potent agonist, playing a significant role in cell signaling pathways, particularly within neuroscience research. Its primary applications involve investigating tachykinin receptor interactions and neuroinflammatory processes in biological systems.

IUPAC
Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Nle-NH2
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[Nle11]-Substance P (C64H100N18O13) — chemical structure, CAS 57462-42-7; Life Science, fine chemical supplied by Tech Serve Solutions
AgonistCell BiologyPeptides and ProteinsPeptides for Cell BiologyTachykinins More...
01 /Applications

Neuroscience Research

Serves as a valuable tool for studying the role of tachykinin receptors in neuronal function and modulation. Investigates pain perception, inflammation, and other neurological processes.

Cell Signaling Studies

Utilised to explore intracellular signaling cascades activated by tachykinin receptor stimulation. Aids in understanding cellular responses to neuropeptides.

Peptide Synthesis and Analysis

Acts as a reference standard in the development and validation of analytical methods for peptide quantification. Useful for research in peptide chemistry.

02 /Properties
Molecular weight1329.59
Empirical formulaC64H100N18O13
Assay≥97% (HPLC)
Storage temperature−20°C
03 /Safety & handling
Protective equipmentEyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
57462-42-7
MDL number
MFCD00076785
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is [Nle11]-Substance P used for?

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[Nle11]-Substance P is primarily used as a potent agonist in neuroscience and cell signaling research, particularly for investigating tachykinin receptor interactions and neuroinflammatory processes.

What is the CAS number and formula for [Nle11]-Substance P?

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The CAS number is 57462-42-7 and the empirical formula is C64H100N18O13.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies [Nle11]-Substance P with an assay of ≥97% (HPLC). This product is intended for research use and is not represented as USP, BP, EP, or any other pharmacopoeia grade.

How should [Nle11]-Substance P be handled safely?

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Handle [Nle11]-Substance P with appropriate personal protective equipment, including eyeshields and gloves. Use a type N95 (US) or type P1 (EN143) respirator filter if airborne exposure is possible. Ensure adequate ventilation. The product has a WGK Germany rating of 3.

How is [Nle11]-Substance P shipped and exported?

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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including [Nle11]-Substance P. We ensure appropriate packaging and documentation for international shipments.

How can I request a sample or quote for [Nle11]-Substance P?

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Please contact our sales team via the website or telephone to request a sample or a quotation for [Nle11]-Substance P.

Need [Nle11]-Substance P in a specific grade or volume?