α-Nicotinamide adenine dinucleotide, reduced disodium salt
α-Nicotinamide adenine dinucleotide, reduced disodium salt (CAS 108321-31-9) is a biochemical cofactor with the molecular formula C21H27N7O14P2Na2. This disodium salt form of α-NADH is essential for various enzymatic reactions, particularly those involving oxidation-reduction processes. It serves as a cosubstrate in biochemical assays to evaluate the kinetics and specificity of NAD+/NADH dependent enzymes and plays a role in studying nucleotide dynamics in ion channels.
- IUPAC
- α-DPNH,α-Dihydrodiphosphopyridine nucleotide,α-Dihydronicotinamide adenine dinucleotide,α-NADH
- Synonyms
- C21H27N7O14P2Na2α-DPNHα-Dihydrodiphosphopyridine nucleotideα-Dihydronicotinamide adenine dinucleotideα-NADH
Enzyme Assays
Used as a cosubstrate to assess the specificity and kinetics of NAD+/NADH dependent enzymes. This allows for detailed characterisation of enzyme activity and reaction mechanisms.
Ion Channel Research
Applicable for studying the dynamics of nucleotides in ion channels, such as voltage-dependent mitochondrial ion channels (VDAC). This aids in understanding cellular energy transport and signalling pathways.
Biochemical Research
Serves as a crucial reagent in various biochemical and metabolic studies, particularly those focusing on redox reactions and cellular energy metabolism.
| Molecular weight | 709.40 |
|---|---|
| Linear formula | C21H27N7O14P2Na2 |
| Assay | ≥90% |
| Storage temperature | −20°C |
| Impurities tested | ≤3% β-isomer |
| Application | α-Nicotinamide adenine dinucleotide, reduced (α-NADH) may be used as a cosubstrate to assess the specificity and kinetics of NAD+/NADH and NADP+/NADPH dependent enzymes and to assess the dynamics of nucleotides in ion channels such as voltage-dependent mitochondrial ion channels (VDAC). |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is α-Nicotinamide adenine dinucleotide, reduced disodium salt used for?
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It is used as a cosubstrate in biochemical assays to assess the specificity and kinetics of NAD+/NADH dependent enzymes and to study nucleotide dynamics in ion channels like voltage-dependent mitochondrial ion channels (VDAC).
What are the CAS number and formula for this product?
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The CAS number is 108321-31-9 and the linear formula is C21H27N7O14P2Na2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of ≥90% and no more than 3% β-isomer. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should α-Nicotinamide adenine dinucleotide, reduced disodium salt be handled?
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Handle with appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. The substance has a WGK rating of 3 in Germany, indicating it is hazardous.
How is this chemical shipped and exported?
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This chemical is stored at -20°C. Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, pharmaceutical intermediates and laboratory reagents.
How can I request a sample or quote?
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Please contact our sales team via the website or direct email to request a sample or obtain a quotation for α-Nicotinamide adenine dinucleotide, reduced disodium salt.
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