Neridronate
Neridronate (CAS 79778-41-9, C6H17NO7P2) is a synthetic bisphosphonate with a molecular weight of 277.15 g/mol. Typically supplied as a white solid, it is known for its applications in bone metabolism research. Neridronate exhibits solubility in water and is stored at refrigerated temperatures (2-8°C). This compound is a valuable reagent for scientific investigation into cellular processes and signalling pathways, particularly those involving bone remodelling.
- IUPAC
- 6-Amino-1-hydroxyhexylidene bisphosphonic acid,Neridronic acid,Nerixia
- Synonyms
- Neridronic acid6-Amino-1-hydroxyhexylidene bisphosphonic acidNerixia
Bone Metabolism Research
Neridronate is utilised in studies investigating bone resorption and formation processes. Its bisphosphonate structure allows it to interact with hydroxyapatite, influencing osteoclast activity.
Cellular Signalling Studies
This compound can be employed as a tool in understanding intracellular signalling cascades, particularly those related to bone homeostasis and mineralisation. It is relevant in research concerning cell biology and cytokine interactions.
Biochemical Assays
As a well-defined chemical entity, Neridronate serves as a standard or control in biochemical assays focusing on phosphonate metabolism or related enzymatic activities.
| Molecular weight | 277.15 |
|---|---|
| Empirical formula | C6H17NO7P2 |
| Assay | ≥97% (NMR) |
| Form | solid |
| Colour | white |
| Solubility | H2O: >5 mg/mL |
| Storage temperature | 2-8°C |
Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Description | may contain <1% (w/w) inorganic salts |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Neridronate used for?
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Neridronate is used in scientific research, particularly in studies related to bone metabolism, cellular signalling, and biochemical assays. TSS supplies this chemical for laboratory and research purposes only.
What are the CAS number and formula for Neridronate?
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The CAS number for Neridronate is 79778-41-9, and its empirical formula is C6H17NO7P2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Neridronate with a purity of ≥97% (NMR). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Neridronate be handled safely?
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Neridronate is classified as a Warning substance (GHS07), and it is harmful if swallowed (H302). Appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves, should be used when handling this chemical. Ensure adequate ventilation.
How is Neridronate packed and shipped?
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Neridronate is typically supplied as a white solid and requires storage at 2-8°C. It is carefully packed for export by Tech Serve Solutions, adhering to relevant shipping regulations for research chemicals.
How can I request a quote or sample for Neridronate?
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To request a quote or a sample of Neridronate, please contact our sales team through the TSS website or via direct inquiry, providing your contact details and intended research application.
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