Nepicastat hydrochloride
Nepicastat hydrochloride (CAS: 170151-24-3) is a chemical compound with the formula C14H15F2N3S · HCl and a molecular weight of 331.81 g/mol. Supplied as a white to beige powder, it is primarily utilised in cell biology, neuroscience research, and studies involving cell signalling. Its function as an enzyme inhibitor, specifically related to dopamine beta-hydroxylase, makes it a valuable tool for investigating neurotransmission and neurotransmitter metabolism pathways. This compound is a hydrochloride salt form.
- IUPAC
- 5-(Aminomethyl)-1-[(2S)-5,7-difluoro-1,2,3,4-tetrahydro-2-naphthalenyl]-1,3-dihydro-2H-imidazole-2-thione hydrochloride,SYN-117

Neuroscience Research
Nepicastat hydrochloride serves as a key reagent in neuroscience research, particularly for studying dopamine beta-hydroxylase activity. It aids in understanding neurotransmitter metabolism and its role in neurological processes.
Cell Signalling Studies
This compound is valuable for investigating cell signalling pathways. Its inhibitory action on specific enzymes allows researchers to probe complex biological mechanisms within cellular systems.
Enzyme Inhibition Studies
As an enzyme inhibitor, Nepicastat hydrochloride is used to explore the function and regulation of enzymes such as dopamine beta-hydroxylase. This helps elucidate biochemical pathways and potential drug targets.
Neurotransmission Research
Researchers utilise Nepicastat hydrochloride to investigate the intricacies of neurotransmission. By modulating dopamine beta-hydroxylase, it offers insights into the synthesis and release of neurotransmitters.
| Molecular weight | 331.81 |
|---|---|
| Empirical formula | C14H15F2N3S · HCl |
| Assay | ≥95% (HPLC) |
| Form | powder |
| Colour | white to beige |
| Solubility | DMSO: soluble10 mg/mL, clear |
| Storage temperature | −20°C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Storage Condition | desiccated |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Nepicastat hydrochloride used for?
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Nepicastat hydrochloride is used in cell biology, cell signalling, neuroscience research, and for studying dopamine beta-hydroxylase, neurotransmission, and neurotransmitter metabolism. It functions as an enzyme inhibitor.
What is the CAS number and formula for Nepicastat hydrochloride?
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The CAS number for Nepicastat hydrochloride is 170151-24-3, and its chemical formula is C14H15F2N3S · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Nepicastat hydrochloride with an assay of ≥95% (HPLC). We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should Nepicastat hydrochloride be handled and stored?
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Nepicastat hydrochloride is a Warning substance. It may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment in a well-ventilated area. Store desiccated at -20°C.
Is Nepicastat hydrochloride shipped internationally?
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Yes, Tech Serve Solutions, established in 1998, is a specialist global supplier and exporter of fine chemicals, including Nepicastat hydrochloride.
How can I request a quote or sample?
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To request a quote or sample of Nepicastat hydrochloride, please contact our sales team through our website or by phone.
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