Nepafenac
Nepafenac (CAS: 78281-72-8), with the molecular formula C15H14N2O2 and a molecular weight of 254.28 g/mol, is a chemical compound supplied by Tech Serve Solutions. This compound typically presents as a faint yellow to dark yellow powder. It is primarily recognised for its role in research related to the arachidonic acid cascade and cell signaling, often utilised as an enzyme inhibitor in biological studies.
- IUPAC
- 2-Amino-3-benzoyl-benzeneacetamide,AHR 9434,AL 6515
- Synonyms
- 2-Amino-3-benzoyl-benzeneacetamide,AHR 9434,AL 6515

Research in Arachidonic Acid Cascade
Nepafenac is utilised in scientific research focused on the arachidonic acid cascade, a critical pathway involved in inflammation and pain signaling. Its properties as an enzyme inhibitor make it a valuable tool for studying these biological processes.
Cell Biology and Signaling Studies
This compound serves as a reagent in cell biology and cell signaling research, particularly in neuroscience. It aids in investigating molecular pathways and cellular responses relevant to various biological functions.
Enzyme Inhibition Research
As an enzyme inhibitor, Nepafenac is employed in laboratory settings to probe the mechanisms of specific enzymes. This application is crucial for understanding enzyme kinetics and developing targeted therapeutic agents.
| Molecular weight | 254.28 |
|---|---|
| Empirical formula | C15H14N2O2 |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | faint yellow to dark yellow |
| Solubility | DMSO: ≥5 mg/mL |
| Storage temperature | room temp |

Hazard statements
- H400Very toxic to aquatic life
Precautionary statements
- P273Avoid release to the environment
| Transport (UN / ADR) | UN 3077 9 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | N |
| Risk statements (R) | 50/53 |
| Safety statements (S) | 60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Nepafenac used for?
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Nepafenac is primarily used in research settings for studies involving the arachidonic acid cascade, cell biology, cell signaling, neuroscience, and as an enzyme inhibitor.
What are the CAS number and molecular formula for Nepafenac?
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The CAS number for Nepafenac is 78281-72-8, and its molecular formula is C15H14N2O2.
What grade and purity does Tech Serve Solutions supply for Nepafenac?
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Tech Serve Solutions supplies Nepafenac with an assay of ≥98% (HPLC). This is a research-grade chemical and not intended for pharmaceutical, food, or therapeutic use.
How should Nepafenac be handled safely?
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Nepafenac is classified under GHS09 with the hazard statement H400 (Very toxic to aquatic life). It is also identified with hazard code N (Dangerous for the environment). Handle with appropriate personal protective equipment and avoid release into the environment. Refer to the Safety Data Sheet for comprehensive handling instructions.
How is Nepafenac packaged and shipped?
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Nepafenac is typically supplied as a powder. It is shipped at room temperature. As per UN 3077 (Class 9, Packing Group III), it is considered an environmentally hazardous substance for transport.
How can I request a sample or quote for Nepafenac?
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To request a sample or a quote for Nepafenac, please contact the Tech Serve Solutions sales team through our website or by phone. Provide the product name and CAS number (78281-72-8) in your request.
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