Neopentyl chloroformate
Neopentyl chloroformate (CAS: 20412-38-8) is a versatile organic compound with the linear formula (CH₃)₃CCH₂OCOCl and a molecular weight of 150.60 g/mol. This acid halide functions as a valuable building block and carbonyl compound in chemical synthesis. It is primarily utilised in organic chemistry for introducing the neopentoxycarbonyl protecting group, offering unique steric properties. Tech Serve Solutions offers this reagent for laboratory and research applications.
- IUPAC
- 2,2-Dimethylpropyl chloroformate
- Synonyms
- 2,2-Dimethylpropyl chloroformate
Protecting Group Chemistry
Neopentyl chloroformate is employed to introduce the neopentoxycarbonyl (Npc) protecting group onto alcohols and amines. This group offers distinct steric hindrance compared to other common carbamates, influencing reaction selectivity and downstream processing.
Organic Synthesis Intermediate
As a reactive acid halide, it serves as a key intermediate in the synthesis of various complex organic molecules. Its structure allows for specific derivatisation in multi-step synthetic pathways.
Research and Development
This compound is utilised in academic and industrial research laboratories for exploring novel synthetic routes and developing new chemical entities. Its application aids in the creation of specialised chemical structures.
| Molecular weight | 150.60 |
|---|---|
| Linear formula | (CH3)3CCH2OCOCl |
| Assay | 97% |
| Boiling point | 55 °C/36 mmHg(lit.) |
| Density | 1.003 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.410(lit.) |
| Vapour pressure | −0.65 psi (20 °C) |
| Storage temperature | 2-8°C |
Hazard statements
- H226Flammable liquid and vapour
- H314Causes severe skin burns and eye damage
- H331Toxic if inhaled
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 32 °C / 89.6 °F |
| Transport (UN / ADR) | UN 2742 6.1(3)(8) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 10-23-34 |
| Safety statements (S) | 16-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Neopentyl chloroformate used for?
+
Neopentyl chloroformate is primarily used as a reagent in organic synthesis to introduce the neopentoxycarbonyl (Npc) protecting group onto alcohols and amines, and as a building block for constructing complex molecules.
What is the CAS number and formula for Neopentyl chloroformate?
+
The CAS number for Neopentyl chloroformate is 20412-38-8, and its linear formula is (CH₃)₃CCH₂OCOCl.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Neopentyl chloroformate with a minimum assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should Neopentyl chloroformate be handled safely?
+
Neopentyl chloroformate is a flammable liquid and causes severe skin burns and eye damage, and is toxic if inhaled. Handle with extreme care, wearing appropriate personal protective equipment including gloves, eye protection, and a respirator. Ensure adequate ventilation and avoid ignition sources.
How is Neopentyl chloroformate packed and shipped?
+
Neopentyl chloroformate is packed according to relevant transportation regulations for hazardous materials. We export globally, adhering to all necessary international shipping and customs requirements.
How can I request a quote or sample?
+
To request a quote or a sample of Neopentyl chloroformate, please contact our sales team through the website or by phone, providing your specific requirements.
▶ Related products
3,4,5-Trimethoxybenzylamine
Organic Building Blocks
3,4-dihydroxyphenylacetone
Organic Building Blocks
3-Fluoro-4-methoxybenzonitrile
C8H6FNO
Organic Building Blocks
4-Ethyltoluene
C2H5C6H4CH3
Organic Building Blocks
Fluoroacetic acid
C2H3FO2
Organic Building Blocks
Methoxyacetaldehyde
C3H6O2
Organic Building Blocks
Methyl 4-acetamido-5-chloro-2-methoxybenzoate
Organic Building Blocks
Methyl 5-bromo-2-iodobenzoate
BrC6H3(I)CO2CH3
Organic Building Blocks▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis