Naphthol AS-GR phosphate disodium salt
Naphthol AS-GR phosphate disodium salt (CAS: 100929-51-9) is a chemical compound with the formula C22H16NO5PNa2 and a molecular weight of 451.32 g/mol. As a disodium salt derivative, it is primarily employed as a chromogenic substrate in various histochemical and cytochemical applications. Its utility lies in its ability to be cleaved by specific enzymes, yielding a coloured precipitate that aids in the identification and localisation of cellular components or enzyme activity.

Histochemistry and Cytochemistry
Naphthol AS-GR phosphate disodium salt serves as a vital substrate in histochemical staining procedures. It is particularly useful for the detection of alkaline phosphatase activity within tissue sections and cell preparations, where enzymatic hydrolysis leads to the formation of a localised coloured product.
Enzyme Assays
This compound is used in biochemical research for the qualitative and quantitative assessment of phosphatase enzyme activity. Upon enzymatic dephosphorylation, it generates a detectable colour, allowing for the monitoring of enzyme kinetics and distribution.
Cell Biology Research
In cell biology, Naphthol AS-GR phosphate disodium salt contributes to the study of cellular processes and enzyme localisation. Its application aids in visualising specific cellular structures or metabolic activities where phosphatase enzymes play a role.
| Molecular weight | 451.32 |
|---|---|
| Linear formula | C22H16NO5PNa2 |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Naphthol AS-GR phosphate disodium salt used for?
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Naphthol AS-GR phosphate disodium salt is used as a chromogenic substrate in histochemistry, cytochemistry, and enzyme assays, primarily for the detection of alkaline phosphatase activity.
What are the CAS number and chemical formula?
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The CAS number for Naphthol AS-GR phosphate disodium salt is 100929-51-9, and its chemical formula is C22H16NO5PNa2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Naphthol AS-GR phosphate disodium salt as a reagent for research and laboratory use. The specific assay and purity are detailed on the product's Certificate of Analysis. TSS does not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions for this product?
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When handling Naphthol AS-GR phosphate disodium salt, it is essential to wear appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The product has a WGK Germany classification of 3, indicating a high hazard to water.
How is this chemical packed and shipped?
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Naphthol AS-GR phosphate disodium salt is carefully packed according to international shipping regulations and is available for global export by Tech Serve Solutions.
How can I request a sample or quote?
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To request a sample or a quote for Naphthol AS-GR phosphate disodium salt, please contact our sales team through the details provided on the Tech Serve Solutions website.
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