N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine
N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine (CAS 64325-78-6) is a protected nucleoside derivative with the molecular formula C38H35N5O6 and a molecular weight of 657.71 g/mol. This compound serves as a crucial building block in oligonucleotide synthesis and chemical biology research. Its protected nature allows for selective modifications and incorporation into DNA or RNA strands, facilitating the study of nucleic acid structure, function, and therapeutic applications.
- IUPAC
- Bz-DMT-dA
- Synonyms
- Bz-DMT-dA2'-Deoxyadenosine, N6-benzoyl-5'-O-(4,4'-dimethoxytrityl)-
Oligonucleotide Synthesis
This protected deoxyadenosine derivative is widely used as a phosphoramidite or H-phosphonate building block in the automated synthesis of DNA oligonucleotides. The dimethoxytrityl (DMT) group provides 5'-OH protection, while the benzoyl group protects the exocyclic amine of adenine.
Chemical Biology Research
It is employed in studies involving modified nucleic acids, DNA probes, and aptamers. Its incorporation allows researchers to investigate gene function, develop diagnostic tools, and engineer novel biomolecules with specific binding or catalytic properties.
Nucleoside Chemistry
As a derivatized nucleoside, it is valuable for synthetic chemists exploring new methodologies for nucleoside modifications and their biological implications. It enables the creation of complex nucleoside analogs for drug discovery.
| Molecular weight | 657.71 |
|---|---|
| Empirical formula | C38H35N5O6 |
| Assay | 98% |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine used for?
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This compound is primarily used as a protected building block in oligonucleotide synthesis and for research in chemical biology and nucleoside chemistry.
What are the CAS number and molecular formula?
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The CAS number is 64325-78-6, and the molecular formula is C38H35N5O6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with a purity of 98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated.
How should N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine be stored and handled?
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This chemical should be stored at -20°C. Appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or P1 (EN143) respirator filter, should be used during handling, as it carries a WGK Germany of 3.
How is this product shipped?
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Tech Serve Solutions, as a global supplier and exporter, packages and ships chemicals in compliance with international regulations for safe transport.
How can I request a sample or quote?
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Please contact our customer service team via phone or email to request a sample or a formal quotation for N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine.
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