Nε-Trifluoroacetyl-L-lysine
Nε-Trifluoroacetyl-L-lysine (CAS: 10009-20-8), with the molecular formula C8H13F3N2O3 and a molecular weight of 242.20 g/mol, is a modified amino acid derivative. It is primarily utilised in chemical synthesis and biochemical research. This compound serves as a valuable building block in peptide chemistry and other organic synthesis applications where the trifluoroacetyl protecting group on the lysine side chain is required.
- IUPAC
- ε-TFA-lysine

Peptide Synthesis
Nε-Trifluoroacetyl-L-lysine is employed as a protected amino acid in solid-phase and solution-phase peptide synthesis. The trifluoroacetyl group offers orthogonal protection strategies, allowing for selective deprotection during complex peptide assembly.
Chemical Synthesis
This compound acts as a versatile intermediate in the synthesis of various organic molecules. Its specific functionalization allows for controlled reactions in the preparation of more complex chemical entities.
Biochemical Research
Utilised in biochemical studies, Nε-Trifluoroacetyl-L-lysine can be incorporated into peptides or proteins to investigate structure-function relationships or to modify biological properties.
| Molecular weight | 242.20 |
|---|---|
| Empirical formula | C8H13F3N2O3 |
| Assay | ≥96.0% (TLC) |
| Solubility | 2 M HCl: soluble10 mg/mL, clear, colorless |
| Storage temperature | 2-8°C |
| Impurities tested | ≤7% water |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 1 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Nε-Trifluoroacetyl-L-lysine used for?
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Nε-Trifluoroacetyl-L-lysine is used in chemical synthesis, peptide chemistry, and biochemical research as a protected amino acid derivative.
What are the CAS number and formula for Nε-Trifluoroacetyl-L-lysine?
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The CAS number is 10009-20-8 and the empirical formula is C8H13F3N2O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Nε-Trifluoroacetyl-L-lysine with an assay of ≥96.0% (TLC). We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling requirements for Nε-Trifluoroacetyl-L-lysine?
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Appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter, should be used. The product has a WGK Germany classification of 1.
How is Nε-Trifluoroacetyl-L-lysine stored and shipped?
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The recommended storage temperature is 2-8°C. Tech Serve Solutions is a global supplier and exporter of fine chemicals.
How can I request a quote or sample for Nε-Trifluoroacetyl-L-lysine?
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Please contact our sales team to request a quote or a sample for Nε-Trifluoroacetyl-L-lysine.
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