Nω-Nitro-L-arginine
Nω-Nitro-L-arginine (CAS: 2149-70-4) is a chemical compound with the formula C6H13N5O4 and a molecular weight of 219.20 g/mol. This arginine analogue functions as a potent inhibitor of nitric oxide synthase (NOS) enzymes. It is recognised for its utility in biochemical research, particularly in studies involving cell signalling, enzyme inhibition, and the investigation of nitric oxide metabolism. Available from TSS, it serves as a valuable reagent for academic and industrial laboratories.
- IUPAC
- L-NNA,N5-(Nitroamidino)-L-2,5-diaminopentanoic acid,NG-NO2-L-Arg
- Synonyms
- L-NNAN5-(Nitroamidino)-L-2,5-diaminopentanoic acidNG-NO2-L-Arg
Nitric Oxide Synthase (NOS) Inhibition
Nω-Nitro-L-arginine is a well-established inhibitor of nitric oxide synthase enzymes. It is widely used in research to modulate nitric oxide production and study its physiological and pathological roles in various biological systems.
Cell Biology Research
This compound serves as a tool in cell biology to investigate the impact of NOS inhibition on cellular processes. Its applications span studies of cell signalling pathways, inflammation, and cardiovascular function.
Biochemical Assays
As a selective enzyme inhibitor, Nω-Nitro-L-arginine is employed in biochemical assays to characterise the activity of NOS isoforms and to understand enzyme kinetics and mechanisms.
| Molecular weight | 219.20 |
|---|---|
| Empirical formula | C6H13N5O4 |
| Assay | ≥99.0% (NT) |
| Optical activity | [α]20/D +24±1°, c = 4% in 2 M HCl |
| Melting point | 255-260 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Ignition residue | ≤0.05% |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... NOS1(4842), NOS2(4843), NOS2B(201288), NOS2C(645740), NOS3(4846)mouse ... Nos2(18126)rat ... Grin2a(24409), Nos1(24598) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Nω-Nitro-L-arginine used for?
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Nω-Nitro-L-arginine is primarily used as an inhibitor of nitric oxide synthase (NOS) enzymes in biochemical and cell biology research to study the roles of nitric oxide.
What are the CAS number and chemical formula for Nω-Nitro-L-arginine?
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The CAS number for Nω-Nitro-L-arginine is 2149-70-4, and its chemical formula is C6H13N5O4.
What grade and purity does Tech Serve Solutions supply for Nω-Nitro-L-arginine?
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Tech Serve Solutions supplies Nω-Nitro-L-arginine with a purity of ≥99.0% (NT). This product is intended for research and laboratory use and is not represented as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling recommendations for Nω-Nitro-L-arginine?
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When handling Nω-Nitro-L-arginine, it is recommended to use safety measures including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. The compound is classified with WGK Germany 3.
How is Nω-Nitro-L-arginine packed, shipped, and exported by TSS?
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Tech Serve Solutions expertly packs, ships, and exports Nω-Nitro-L-arginine globally, adhering to all necessary regulations for chemical transport to ensure safe and timely delivery to your research facility.
How can I request a sample or quote for Nω-Nitro-L-arginine?
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To request a sample or a detailed quote for Nω-Nitro-L-arginine, please contact our sales team through the website or by phone. We are happy to assist with your specific research needs.
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