N-Succinyl-Leu-Tyr-7-amido-4-methylcoumarin

CAS 94367-20-1C29H33N3O8Biochemicals & Reagents

N-Succinyl-Leu-Tyr-7-amido-4-methylcoumarin (CAS: 94367-20-1) is a fluorogenic peptide substrate with the empirical formula C29H33N3O8 and a molecular weight of 551.59 g/mol. This compound is primarily employed in biochemical research for the detection and quantification of specific enzyme activities. Its structure allows for sensitive fluorescence measurements upon enzymatic cleavage, making it valuable in studies related to cell signalling and apoptosis.

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N-Succinyl-Leu-Tyr-7-amido-4-methylcoumarin (C29H33N3O8) — chemical structure, CAS 94367-20-1; Life Science, fine chemical supplied by Tech Serve Solutions

Apoptosis EnzymesApplication IndexBiochemicals and ReagentsCalpainCell BiologyCell Signaling EnzymesEnzyme SubstratesEnzymesInhibitorsand Substrates

01 /Applications

Enzyme Activity Assays

Used as a fluorogenic substrate to measure the activity of specific proteases, particularly calpains. The release of fluorescent 7-amino-4-methylcoumarin upon cleavage allows for sensitive detection of enzyme kinetics.

Cell Biology Research

Facilitates research into cellular processes such as apoptosis and cell signalling by enabling the monitoring of enzyme function within cellular environments. Its application in cell signalling enzyme studies is noteworthy.

Protease Characterisation

A valuable tool for characterising the specificity and activity profiles of various proteases, including those involved in proteasome and lysosomal pathways. This aids in understanding enzyme mechanisms.

02 /Properties

Molecular weight	551.59
Empirical formula	C29H33N3O8
Storage temperature	−20°C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

94367-20-1

MDL number

MFCD00057900

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is N-Succinyl-Leu-Tyr-7-amido-4-methylcoumarin used for?

N-Succinyl-Leu-Tyr-7-amido-4-methylcoumarin is used as a fluorogenic substrate in biochemical research to assay the activity of specific proteases, such as calpains, and to study cell biology processes like apoptosis and cell signalling.

What is the CAS number and formula for N-Succinyl-Leu-Tyr-7-amido-4-methylcoumarin?

The CAS number is 94367-20-1 and the empirical formula is C29H33N3O8.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this product for research and laboratory use. Purity and specific grades are detailed on the product's Certificate of Analysis. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.

How should N-Succinyl-Leu-Tyr-7-amido-4-methylcoumarin be handled and stored?

Handle with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Store at -20°C. Refer to the Safety Data Sheet for comprehensive handling information. It carries a WGK Germany rating of 3.

Is this product suitable for export?

Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents, including N-Succinyl-Leu-Tyr-7-amido-4-methylcoumarin.